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Head-to-head for women

RxSpan MD vs Effecty

RxSpan MD and Effecty both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

RxSpan MD

Ranked #10 for women · Grade B

Best for: Women who prioritize an accredited, brand-capable program with an oral route and don't mind paying at the higher end.

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vs

Effecty

Higher score

Ranked #6 for women · Grade B+

Best for: Women who want the flexibility of both compounded and FDA-approved brand medication from a LegitScript-accredited, nationwide provider.

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The verdict for women

Higher Luna Fit Score: Effecty

Effecty edges out RxSpan MD on the Luna Fit Score, 87 to 86 (B+ vs B). Women who want the flexibility of both compounded and FDA-approved brand medication from a LegitScript-accredited, nationwide provider.

RxSpan MD is still a genuine option — a full-service, accredited program with brand access and an oral option — the trade-off is premium pricing, which buys breadth rather than a bargain. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

RxSpan MD Effecty
PCOS & hormonal suitability8686
RxSpan
Effecty
Clinical oversight & labs8888
RxSpan
Effecty
Price transparency8085
RxSpan
Effecty
Nationwide access9595
RxSpan
Effecty
Ongoing support8484
RxSpan
Effecty
Cancellation fairness8383
RxSpan
Effecty

Price, access & features

DetailRxSpan MDEffecty
Luna Fit Score86/100 · B87/100 · B+
Overall rank#10#6
Semaglutide$249/mo$160/mo
Tirzepatide$329/mo$240/mo
CoverageAll 50 statesAll 50 states
Brand-name accessYesYes
Oral / sublingualYesInjection only

RxSpan MD

Ranked #10 · Grade B

What we like

  • FDA-approved brand access, oral option, and both molecules on one account
  • LegitScript-accredited, nationwide across all 50 states
  • Comprehensive feature set for women who want every option available

The caveats

  • Highest-tier pricing among the accredited options — $249 semaglutide, $329 tirzepatide
  • General metabolic program, not hormone-specialized

Effecty

Ranked #6 · Grade B+

What we like

  • FDA-approved brand access plus compounded, both molecules
  • LegitScript-accredited — a meaningful oversight signal when hormones are involved
  • Nationwide across all 50 states

The caveats

  • No oral/sublingual form
  • Not a hormone-specialty program; PCOS framing is general

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing RxSpan MD and Effecty against other providers we review for women.

Or browse the full comparison hub.