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Head-to-head for women

Vaylen vs RxSpan MD

Vaylen and RxSpan MD both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Vaylen

Higher score

Ranked #7 for women · Grade B+

Best for: Women who want maximum optionality — injectable or oral, compounded or brand — from an accredited, all-50-states provider.

Visit Vaylen
vs

RxSpan MD

Ranked #10 for women · Grade B

Best for: Women who prioritize an accredited, brand-capable program with an oral route and don't mind paying at the higher end.

Visit RxSpan MD

The verdict for women

Higher Luna Fit Score: Vaylen

Vaylen edges out RxSpan MD on the Luna Fit Score, 87 to 86 (B+ vs B). Women who want maximum optionality — injectable or oral, compounded or brand — from an accredited, all-50-states provider.

RxSpan MD is still a genuine option — a full-service, accredited program with brand access and an oral option — the trade-off is premium pricing, which buys breadth rather than a bargain. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Vaylen RxSpan MD
PCOS & hormonal suitability8686
Vaylen
RxSpan
Clinical oversight & labs8888
Vaylen
RxSpan
Price transparency8480
Vaylen
RxSpan
Nationwide access9595
Vaylen
RxSpan
Ongoing support8484
Vaylen
RxSpan
Cancellation fairness8383
Vaylen
RxSpan

Price, access & features

DetailVaylenRxSpan MD
Luna Fit Score87/100 · B+86/100 · B
Overall rank#7#10
Semaglutide$179/mo$249/mo
Tirzepatide$239/mo$329/mo
CoverageAll 50 statesAll 50 states
Brand-name accessYesYes
Oral / sublingualYesYes

Vaylen

Ranked #7 · Grade B+

What we like

  • Offers an oral/sublingual route as well as injections — real choice for the needle-averse
  • FDA-approved brand access plus compounded on both molecules
  • LegitScript-accredited and available in all 50 states

The caveats

  • Mid-tier pricing rather than the cheapest tiers
  • Broad program rather than a dedicated PCOS/hormone clinic

RxSpan MD

Ranked #10 · Grade B

What we like

  • FDA-approved brand access, oral option, and both molecules on one account
  • LegitScript-accredited, nationwide across all 50 states
  • Comprehensive feature set for women who want every option available

The caveats

  • Highest-tier pricing among the accredited options — $249 semaglutide, $329 tirzepatide
  • General metabolic program, not hormone-specialized

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing Vaylen and RxSpan MD against other providers we review for women.

Or browse the full comparison hub.