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Head-to-head for women

MadeMed vs Vaylen

MadeMed and Vaylen both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

MadeMed

Ranked #6 for women · Grade B

Best for: Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider.

Visit MadeMed
vs

Vaylen

Higher score

Ranked #22 for women · Grade B+

Best for: Women who want maximum optionality — injectable or oral, compounded or brand — from an accredited, all-50-states provider.

Visit Vaylen

The verdict for women

Higher Luna Fit Score: Vaylen

Vaylen edges out MadeMed on the Luna Fit Score, 87 to 84 (B+ vs B). Women who want maximum optionality — injectable or oral, compounded or brand — from an accredited, all-50-states provider. The reasoning behind that number is in what we found reviewing Vaylen.

MadeMed is still a genuine option — a LegitScript-verified compounded program that charges one flat price at every dose — so titrating up to a working dose never quietly raises the bill. Weigh the six women's-health factors below against your own priorities; what we found reviewing MadeMed goes through each of them, and if neither of these two is the one, what women pick instead of MadeMed widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

MadeMed Vaylen
PCOS & hormonal suitability8286
MadeMed
Vaylen
Clinical oversight & labs8088
MadeMed
Vaylen
Price transparency9584
MadeMed
Vaylen
Nationwide access8495
MadeMed
Vaylen
Ongoing support8084
MadeMed
Vaylen
Cancellation fairness8483
MadeMed
Vaylen

Price, access & features

DetailMadeMedVaylen
Luna Fit Score84/100 · B87/100 · B+
Overall rank#6#22
Semaglutide$239/mo quarterly (from $199/mo on 6 months)$179/mo
Tirzepatide$399/mo quarterly (from $369/mo on 6 months)$239/mo
Coverage40 statesAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes

MadeMed

Ranked #6 · Grade B

What we like

  • One price at every dose, published dose by dose — semaglutide $239/mo from 0.25mg to 2.4mg, tirzepatide $399/mo from 2.5mg to 15mg
  • LegitScript verified, with board-certified physician review and US compounding pharmacies
  • Oral semaglutide and oral tirzepatide are both offered alongside the injections

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • 40 states rather than nationwide — check yours before you start
  • Tirzepatide is among the pricier entries in this ranking at $399/mo quarterly

Vaylen

Ranked #22 · Grade B+

What we like

  • Offers an oral/sublingual route as well as injections — real choice for the needle-averse
  • FDA-approved brand access plus compounded on both molecules
  • LegitScript-accredited and available in all 50 states

The caveats

  • Mid-tier pricing rather than the cheapest tiers
  • Broad program rather than a dedicated PCOS/hormone clinic

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither MadeMed nor Vaylen is only worth comparing with the other. MadeMed is also written up against CoreAge Rx, 9 points apart on the Luna Fit Score — see MadeMed vs CoreAge Rx for women. Vaylen is also written up against Effecty, another exact tie — see the Vaylen–Effecty head-to-head.

Or browse the full comparison hub.