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Head-to-head for women
Direct Meds vs MyDrHank
Direct Meds and MyDrHank both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Direct Meds
Higher scoreRanked #26 for women · Grade B−
Luna Fit
Best for: Women who want an oral or sublingual alternative to weekly shots, on an all-inclusive program with no membership fee, and who are comfortable vetting a newer compounder themselves.
FDA warning letterSeptember 2025Read it ↗Visit Direct MedsMyDrHank
Ranked #49 for women · Grade C
Luna Fit
Best for: Readers treating insulin resistance who want tirzepatide at a price that does not climb with the dose, and who will open the plan selector and pay the month-to-month rate rather than the advertised one.
Visit MyDrHankThe verdict for women
Direct Meds edges out MyDrHank on the Luna Fit Score, 80 to 73 (B− vs C). Women who want an oral or sublingual alternative to weekly shots, on an all-inclusive program with no membership fee, and who are comfortable vetting a newer compounder themselves. The reasoning behind that number is in what we found reviewing Direct Meds.
MyDrHank is still a genuine option — a flat, all-dose price on both molecules — including the tirzepatide most insulin-resistance readers are actually here for — from a general telehealth shop that publishes its ladder openly but shows you only the twelve-month rung of it. Weigh the six women's-health factors below against your own priorities; our MyDrHank write-up for women goes through each of them, and if neither of these two is the one, what women pick instead of MyDrHank widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Direct Meds | MyDrHank |
|---|---|---|
| Luna Fit Score | 80/100 · B− | 73/100 · C |
| Overall rank | #26 | #49 |
| Semaglutide | $249/mo sublingual · $297/mo injectable | $259/mo month-to-month (from $178/mo on a 12-month prepay, $2,140 up front) — the site displays only the prepay rate |
| Tirzepatide | $299/mo sublingual · $399/mo injectable | $349/mo month-to-month (from $240/mo on a 12-month prepay, $2,883 up front) — the site displays only the prepay rate |
| Coverage | Not publicly listed | No state list published; its affiliate terms exclude Kansas, Louisiana, Mississippi, New Mexico, North Dakota and West Virginia |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Luna Fit
Direct Meds
Ranked #26 · Grade B−
What we like
- Rare oral and sublingual route in addition to injectable — a real option for the needle-averse
- Both molecules offered — semaglutide and tirzepatide for insulin-resistant PCOS
- All-inclusive pricing with no separate membership fee, and a promotional entry near $147
The caveats
- Compounded only — no FDA-approved brand semaglutide or tirzepatide
- Prices are company-stated, not ones we could verify live, and the brand runs multiple domains
- A newer operator with an ambiguous footprint, so the oversight signal is thinner
Luna Fit
MyDrHank
Ranked #49 · Grade C
What we like
- Tirzepatide is a first-class option here, not an upsell — the dual GIP/GLP-1 agonist is the one most readers arriving on insulin-resistance questions ask about by name
- The price does not move with the dose: its GLP-1 FAQ states "the price stays the same at every dose — no surprise price increases", so a titration to a higher dose does not re-price the plan
- Prices are published before any intake quiz — the full four-rung ladder for every product, with the up-front total beside each per-month figure, rather than a number you have to qualify for
The caveats
- Every price the site displays is the TWELVE-MONTH PREPAY rate — the renderer takes the cheapest rung of the ladder — so the month-to-month figures ($349 tirzepatide, $259 semaglutide) are shown on no page at all
- Its own footnote advertises a tirzepatide price that exists at no tier: "Plans start at $171/mo for compounded semaglutide and $200/mo for compounded tirzepatide" — $200 appears exactly once in the entire site bundle and no tirzepatide rung costs it; the $171 in the same sentence is the ORAL product's yearly rate, while injectable semaglutide's is $178
- The GLP-1 FAQ calls a prepaid annual rate a plan with "no contract", which is true of the paperwork and misleading about the money
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Direct Meds nor MyDrHank is only worth comparing with the other. Direct Meds is also written up against CoreAge Rx, 13 points apart on the Luna Fit Score — see Direct Meds vs CoreAge Rx for women. MyDrHank is also written up against CoreAge Rx, 20 points apart — see MyDrHank against CoreAge Rx, factor by factor.
- Direct Meds vs CoreAge Rx
- Direct Meds vs Enhance MD
- Direct Meds vs Eden
- MyDrHank vs yourEra
- MyDrHank vs Sesame Care
- MyDrHank vs HealthRX
Or browse the full comparison hub.