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Head-to-head for women

Enhance MD vs Fresh Day Meds

Enhance MD and Fresh Day Meds both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Enhance MD

Higher score

Ranked #2 for women · Grade A−

Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

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vs

Fresh Day Meds

Ranked #51 for women · Grade C

Best for: Women transferring an existing GLP-1 prescription who want a standard dose at a low month-to-month price and will read a subscription-terms page carefully.

Visit Fresh Day Meds

The verdict for women

Higher Luna Fit Score: Enhance MD

Enhance MD edges out Fresh Day Meds on the Luna Fit Score, 92 to 71 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.

Fresh Day Meds is still a genuine option — publishes its entire plan matrix in its own subscription terms — every tier, every dose band, every billing cadence — and then locks your price when the dose goes up, which is rarer than it sounds. Weigh the six women's-health factors below against your own priorities; what we found reviewing Fresh Day Meds goes through each of them, and if neither of these two is the one, the alternatives to Fresh Day Meds we rank for women widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Enhance MD Fresh Day Meds
PCOS & hormonal suitability9262
Enhance
Fresh
Clinical oversight & labs9474
Enhance
Fresh
Price transparency9466
Enhance
Fresh
Nationwide access9584
Enhance
Fresh
Ongoing support8876
Enhance
Fresh
Cancellation fairness8566
Enhance
Fresh

Price, access & features

DetailEnhance MDFresh Day Meds
Luna Fit Score92/100 · A−71/100 · C
Overall rank#2#51
Semaglutide$212/mo$140/mo standard doses, no commitment (from $99/mo microdose on a 3-month prepay); renews every 23 days
Tirzepatide$280/mo$179/mo standard doses, no commitment (from $140/mo microdose on a 3-month prepay); renews every 23 days
CoverageAll 50 states48 states and DC (not Arkansas or Virginia)
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only

Enhance MD

Ranked #2 · Grade A−

What we like

  • Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
  • Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
  • Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • No brand-name path and no oral or sublingual route for the needle-averse
  • Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start

Fresh Day Meds

Ranked #51 · Grade C

What we like

  • Publishes the full price matrix — one-month, three-month, new-patient and transfer, for both molecules — inside its own subscription terms rather than in marketing copy
  • Price lock: your rate does not rise when your prescribed dose increases at renewal
  • A genuine no-commitment standard-dose option at $140 semaglutide and $179 tirzepatide for transfers

The caveats

  • The advertised $99 and $140 headline rates are microdose tiers on a three-month prepay — roughly a tenth of a standard dose
  • Plans renew every 23 days rather than monthly, so the effective annual cost is about 9% above the '/mo' figure
  • A $75 non-refundable consultation fee if you miss the physician's callback, and the order is cancelled

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Enhance MD nor Fresh Day Meds is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. Fresh Day Meds is also written up against CoreAge Rx, 22 points apart — see how Fresh Day Meds and CoreAge Rx compare on the Luna Fit Score.

Or browse the full comparison hub.