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Head-to-head for women

Enhance MD vs HumeCare+

Enhance MD and HumeCare+ both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Enhance MD

Higher score

Ranked #2 for women · Grade A−

Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

Visit Enhance MD
vs

HumeCare+

Ranked #50 for women · Grade C

Best for: Women who care more about how much of the loss is muscle than about the headline rate, and who will accept an assessment before seeing a number.

Visit HumeCare+

The verdict for women

Higher Luna Fit Score: Enhance MD

Enhance MD edges out HumeCare+ on the Luna Fit Score, 92 to 73 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.

HumeCare+ is still a genuine option — the only desk here that titrates against lean mass rather than scale weight — a weekly body scan is included — and the only one that will not tell you a price before you finish its assessment. Weigh the six women's-health factors below against your own priorities; the HumeCare+ scorecard goes through each of them, and if neither of these two is the one, the full field we rank against HumeCare+ widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Enhance MD HumeCare+
PCOS & hormonal suitability9278
Enhance
HumeCare+
Clinical oversight & labs9484
Enhance
HumeCare+
Price transparency9438
Enhance
HumeCare+
Nationwide access9570
Enhance
HumeCare+
Ongoing support8888
Enhance
HumeCare+
Cancellation fairness8582
Enhance
HumeCare+

Price, access & features

DetailEnhance MDHumeCare+
Luna Fit Score92/100 · A−73/100 · C
Overall rank#2#50
Semaglutide$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay$199/mo month-to-month at checkout, injection or oral — the marketing site publishes no price at all
Tirzepatide$329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay$299/mo month-to-month with B12 and glycine — priced past the intake, absent from the marketing site
CoverageAll 50 statesNot disclosed
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes

Enhance MD

Ranked #2 · Grade A−

What we like

  • Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
  • Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
  • Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • No brand-name path and no oral or sublingual route for the needle-averse
  • Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start

HumeCare+

Ranked #50 · Grade C

What we like

  • Titrates against fat and lean mass measured weekly at home rather than against the scale — the one thing this category almost never does
  • Includes a body-composition device with the program at no separate charge
  • Builds glycine, B12 and B6 into the protocol for muscle preservation and side effects, rather than selling them as an upsell

The caveats

  • ⚠ Publishes no price anywhere on its marketing site — the figures above are reachable only by completing the assessment
  • ⚠ "From $199" is the semaglutide rung, not the program: tirzepatide is $299, and it is sold without appearing on the marketing site at all
  • ⚠ $199 is a floor rather than a rate — a non-refundable fee is charged at enrollment and again at every refill, and the site does not print it

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Enhance MD nor HumeCare+ is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. HumeCare+ is also written up against CoreAge Rx, 20 points apart — see the HumeCare+–CoreAge Rx head-to-head.

Or browse the full comparison hub.