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Head-to-head for women
Enhance MD vs Prime Doctor RX
Enhance MD and Prime Doctor RX both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Enhance MD
Higher scoreRanked #2 for women · Grade A−
Luna Fit
Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Visit Enhance MDPrime Doctor RX
Ranked #73 for women · Grade C
Luna Fit
Best for: A woman who wants hormone care and weight care from one clinic, and who will convert every figure into four-week cycles before comparing it.
Visit Prime Doctor RXThe verdict for women
Enhance MD edges out Prime Doctor RX on the Luna Fit Score, 92 to 70 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.
Prime Doctor RX is still a genuine option — the only one of this batch running a priced hormone line beside the GLP-1s — and the only one whose "month" is 28 days. Weigh the six women's-health factors below against your own priorities; the Prime Doctor RX scorecard goes through each of them, and if neither of these two is the one, our ranked shortlist of Prime Doctor RX alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Enhance MD | Prime Doctor RX |
|---|---|---|
| Luna Fit Score | 92/100 · A− | 70/100 · C |
| Overall rank | #2 | #73 |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $249 every four weeks — thirteen charges a year, not twelve |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $339 every four weeks — thirteen charges a year, not twelve |
| Coverage | All 50 states | Confirmed during the intake, never published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Luna Fit
Enhance MD
Ranked #2 · Grade A−
What we like
- Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
- Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
- Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- No brand-name path and no oral or sublingual route for the needle-averse
- Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start
Luna Fit
Prime Doctor RX
Ranked #73 · Grade C
What we like
- Runs a hormone-care line alongside the weight-loss program, with initial labs priced at $50 rather than left unstated
- The full ladder for all three weight-loss products and for the hormone line sits on the homepage before any intake
- Every card's footnote says the starting price is the 52-week prepay, in full
The caveats
- The billing cycle is 28 days and every price is labeled per month; $3,497 divided by thirteen is exactly $269, and nothing on the page divides cleanly by calendar months
- A year of month-to-month tirzepatide therefore costs $4,407, not the $4,068 the labels imply
- The $269 and $179 headlines are 52-week prepays; month to month they are $339 and $249
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Enhance MD nor Prime Doctor RX is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. Prime Doctor RX is also written up against CoreAge Rx, 23 points apart — see Prime Doctor RX against CoreAge Rx, factor by factor.
- Enhance MD vs CoreAge Rx
- Enhance MD vs Eden
- Enhance MD vs yourEra
- Prime Doctor RX vs Sesame Care
- Prime Doctor RX vs HealthRX
- Prime Doctor RX vs MadeMed
Or browse the full comparison hub.