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Head-to-head for women

He & She MD vs HumeCare+

He & She MD and HumeCare+ both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

He & She MD

Higher score

Ranked #25 for women · Grade B−

Best for: Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length.

Visit He & She MD
vs

HumeCare+

Ranked #50 for women · Grade C

Best for: Women who care more about how much of the loss is muscle than about the headline rate, and who will accept an assessment before seeing a number.

Visit HumeCare+

The verdict for women

Higher Luna Fit Score: He & She MD

He & She MD edges out HumeCare+ on the Luna Fit Score, 80 to 73 (B− vs C). Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length. The reasoning behind that number is in the He & She MD scorecard.

HumeCare+ is still a genuine option — the only desk here that titrates against lean mass rather than scale weight — a weekly body scan is included — and the only one that will not tell you a price before you finish its assessment. Weigh the six women's-health factors below against your own priorities; the HumeCare+ scorecard goes through each of them, and if neither of these two is the one, the full field we rank against HumeCare+ widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

He & She MD HumeCare+
PCOS & hormonal suitability8878
He
HumeCare+
Clinical oversight & labs7884
He
HumeCare+
Price transparency7238
He
HumeCare+
Nationwide access8470
He
HumeCare+
Ongoing support7688
He
HumeCare+
Cancellation fairness8082
He
HumeCare+

Price, access & features

DetailHe & She MDHumeCare+
Luna Fit Score80/100 · B−73/100 · C
Overall rank#25#50
Semaglutide$199/mo month-to-month ($1,188 once for a year is the $99/mo on the banners)$199/mo month-to-month at checkout, injection or oral — the marketing site publishes no price at all
Tirzepatide$299/mo month-to-month ($1,908 committed for the year)$299/mo month-to-month with B12 and glycine — priced past the intake, absent from the marketing site
CoverageEvery US state except Louisiana for GLP-1s; hormone and longevity lines ship nationwideNot disclosed
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes

He & She MD

Ranked #25 · Grade B−

What we like

  • Sells estradiol (patch, gel and pill) and progesterone alongside its GLP-1s, so the menopause and metabolic sides run through one intake
  • Prices four commitment terms per GLP-1 molecule in public, with the amount actually charged printed beside each
  • Names the dispensing pharmacy in full — F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield OH 45014, with a phone number

The caveats

  • ⚠ The menopause line is the one place it stops publishing terms: estradiol patch, gel and pill and the progesterone pill all show "Starting at $125/month" with no term table at all, while seven other product pages carry a full four-rung ladder
  • ⚠ Every advertised GLP-1 figure is the twelve-month rung — the "$99/month" on the banners requires $1,188 paid once, and the rate you can stop after a month is $199
  • Its FAQ says the pharmacy it names is licensed in 44 states and cannot dispense sterile compounds; a weekly GLP-1 injection is a sterile compound, and a second pharmacy is named in the same answer without saying which fills what

HumeCare+

Ranked #50 · Grade C

What we like

  • Titrates against fat and lean mass measured weekly at home rather than against the scale — the one thing this category almost never does
  • Includes a body-composition device with the program at no separate charge
  • Builds glycine, B12 and B6 into the protocol for muscle preservation and side effects, rather than selling them as an upsell

The caveats

  • ⚠ Publishes no price anywhere on its marketing site — the figures above are reachable only by completing the assessment
  • ⚠ "From $199" is the semaglutide rung, not the program: tirzepatide is $299, and it is sold without appearing on the marketing site at all
  • ⚠ $199 is a floor rather than a rate — a non-refundable fee is charged at enrollment and again at every refill, and the site does not print it

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither He & She MD nor HumeCare+ is only worth comparing with the other. He & She MD is also written up against CoreAge Rx, 13 points apart on the Luna Fit Score — see He & She MD against CoreAge Rx, factor by factor. HumeCare+ is also written up against CoreAge Rx, 20 points apart — see the HumeCare+–CoreAge Rx head-to-head.

Or browse the full comparison hub.