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Head-to-head for women

He & She MD vs Nolu

He & She MD and Nolu both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

He & She MD

Higher score

Ranked #25 for women · Grade B−

Best for: Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length.

Visit He & She MD
vs

Nolu

Ranked #63 for women · Grade C

Best for: Women who want an all-in per-order price with no separate membership fee and are comfortable with general wellness branding rather than a hormone-specialized clinic.

Visit Nolu

The verdict for women

Higher Luna Fit Score: He & She MD

He & She MD edges out Nolu on the Luna Fit Score, 80 to 75 (B− vs C). Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length. The reasoning behind that number is in the He & She MD scorecard.

Nolu is still a genuine option — a wellness-lifestyle brand, not positioned around either gender, selling both molecules plus a named Microdose GLP-1+B12/NAD+ stack in two variants at one all-in price — with no named clinician or pharmacy behind any of it. Weigh the six women's-health factors below against your own priorities; the Nolu scorecard goes through each of them, and if neither of these two is the one, the full field we rank against Nolu widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

He & She MD Nolu
PCOS & hormonal suitability8868
He
Nolu
Clinical oversight & labs7868
He
Nolu
Price transparency7272
He
Nolu
Nationwide access8493
He
Nolu
Ongoing support7678
He
Nolu
Cancellation fairness8075
He
Nolu

Price, access & features

DetailHe & She MDNolu
Luna Fit Score80/100 · B−75/100 · C
Overall rank#25#63
Semaglutide$199/mo month-to-month ($1,188 once for a year is the $99/mo on the banners)$249/mo injectable, or $279/mo oral (billed per 4-week cycle, not calendar month)
Tirzepatide$299/mo month-to-month ($1,908 committed for the year)$339/mo injectable (billed per 4-week cycle, not calendar month)
CoverageEvery US state except Louisiana for GLP-1s; hormone and longevity lines ship nationwideAll 50 states plus Washington D.C. (standard hedge language)
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes

He & She MD

Ranked #25 · Grade B−

What we like

  • Sells estradiol (patch, gel and pill) and progesterone alongside its GLP-1s, so the menopause and metabolic sides run through one intake
  • Prices four commitment terms per GLP-1 molecule in public, with the amount actually charged printed beside each
  • Names the dispensing pharmacy in full — F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield OH 45014, with a phone number

The caveats

  • The menopause line is the one place it stops publishing terms: estradiol patch, gel and pill and the progesterone pill all show "Starting at $125/month" with no term table at all, while seven other product pages carry a full four-rung ladder
  • Every advertised GLP-1 figure is the twelve-month rung — the "$99/month" on the banners requires $1,188 paid once, and the rate you can stop after a month is $199
  • Its FAQ says the pharmacy it names is licensed in 44 states and cannot dispense sterile compounds; a weekly GLP-1 injection is a sterile compound, and a second pharmacy is named in the same answer without saying which fills what

Nolu

Ranked #63 · Grade C

What we like

  • Both molecules plus an oral semaglutide route, and a named Microdose GLP-1+B12/NAD+ stack (two variants) for a gentler on-ramp
  • All-in per-order pricing — consultation, medication and shipping in one figure, with no separate membership fee stacked on top
  • LegitScript verified, and available in all 50 states plus Washington D.C.

The caveats

  • No named medical director, prescribers, or compounding pharmacy disclosed anywhere on the site
  • Billed per 4-week cycle, not calendar month — the real annualized cost runs roughly 8% above what the headline monthly figures imply
  • No PCOS, perimenopause or menopause program — general wellness-lifestyle branding rather than a women's-health-specific clinic

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither He & She MD nor Nolu is only worth comparing with the other. He & She MD is also written up against CoreAge Rx, 13 points apart on the Luna Fit Score — see He & She MD against CoreAge Rx, factor by factor. Nolu is also written up against CoreAge Rx, 18 points apart — see the Nolu–CoreAge Rx head-to-head.

Or browse the full comparison hub.