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Head-to-head for women
He & She MD vs Prime Doctor RX
He & She MD and Prime Doctor RX both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
He & She MD
Higher scoreRanked #25 for women · Grade B−
Luna Fit
Best for: Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length.
Visit He & She MDPrime Doctor RX
Ranked #73 for women · Grade C
Luna Fit
Best for: A woman who wants hormone care and weight care from one clinic, and who will convert every figure into four-week cycles before comparing it.
Visit Prime Doctor RXThe verdict for women
He & She MD edges out Prime Doctor RX on the Luna Fit Score, 80 to 70 (B− vs C). Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length. The reasoning behind that number is in the He & She MD scorecard.
Prime Doctor RX is still a genuine option — the only one of this batch running a priced hormone line beside the GLP-1s — and the only one whose "month" is 28 days. Weigh the six women's-health factors below against your own priorities; the Prime Doctor RX scorecard goes through each of them, and if neither of these two is the one, our ranked shortlist of Prime Doctor RX alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | He & She MD | Prime Doctor RX |
|---|---|---|
| Luna Fit Score | 80/100 · B− | 70/100 · C |
| Overall rank | #25 | #73 |
| Semaglutide | $199/mo month-to-month ($1,188 once for a year is the $99/mo on the banners) | $249 every four weeks — thirteen charges a year, not twelve |
| Tirzepatide | $299/mo month-to-month ($1,908 committed for the year) | $339 every four weeks — thirteen charges a year, not twelve |
| Coverage | Every US state except Louisiana for GLP-1s; hormone and longevity lines ship nationwide | Confirmed during the intake, never published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Luna Fit
He & She MD
Ranked #25 · Grade B−
What we like
- Sells estradiol (patch, gel and pill) and progesterone alongside its GLP-1s, so the menopause and metabolic sides run through one intake
- Prices four commitment terms per GLP-1 molecule in public, with the amount actually charged printed beside each
- Names the dispensing pharmacy in full — F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield OH 45014, with a phone number
The caveats
- The menopause line is the one place it stops publishing terms: estradiol patch, gel and pill and the progesterone pill all show "Starting at $125/month" with no term table at all, while seven other product pages carry a full four-rung ladder
- Every advertised GLP-1 figure is the twelve-month rung — the "$99/month" on the banners requires $1,188 paid once, and the rate you can stop after a month is $199
- Its FAQ says the pharmacy it names is licensed in 44 states and cannot dispense sterile compounds; a weekly GLP-1 injection is a sterile compound, and a second pharmacy is named in the same answer without saying which fills what
Luna Fit
Prime Doctor RX
Ranked #73 · Grade C
What we like
- Runs a hormone-care line alongside the weight-loss program, with initial labs priced at $50 rather than left unstated
- The full ladder for all three weight-loss products and for the hormone line sits on the homepage before any intake
- Every card's footnote says the starting price is the 52-week prepay, in full
The caveats
- The billing cycle is 28 days and every price is labeled per month; $3,497 divided by thirteen is exactly $269, and nothing on the page divides cleanly by calendar months
- A year of month-to-month tirzepatide therefore costs $4,407, not the $4,068 the labels imply
- The $269 and $179 headlines are 52-week prepays; month to month they are $339 and $249
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither He & She MD nor Prime Doctor RX is only worth comparing with the other. He & She MD is also written up against CoreAge Rx, 13 points apart on the Luna Fit Score — see He & She MD against CoreAge Rx, factor by factor. Prime Doctor RX is also written up against CoreAge Rx, 23 points apart — see Prime Doctor RX against CoreAge Rx, factor by factor.
- He & She MD vs CoreAge Rx
- He & She MD vs Enhance MD
- He & She MD vs Eden
- Prime Doctor RX vs yourEra
- Prime Doctor RX vs Sesame Care
- Prime Doctor RX vs HealthRX
Or browse the full comparison hub.