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Head-to-head for women

MadeMed vs Synergy Rx

MadeMed and Synergy Rx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

MadeMed

Higher score

Ranked #7 for women · Grade B

Best for: Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider.

Visit MadeMed
vs

Synergy Rx

Ranked #44 for women · Grade C

Best for: Women who specifically want a brand-name path and unlimited clinical contact, and who are prepared to get pricing by enquiry.

Visit Synergy Rx

The verdict for women

Higher Luna Fit Score: MadeMed

MadeMed edges out Synergy Rx on the Luna Fit Score, 84 to 76 (B vs C). Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider. The reasoning behind that number is in what we found reviewing MadeMed.

Synergy Rx is still a genuine option — one of the few programs here that will prescribe brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited 24/7 access to its clinical team — though you will not find a GLP-1 price anywhere on its site. Weigh the six women's-health factors below against your own priorities; our Synergy Rx write-up for women goes through each of them, and if neither of these two is the one, the Synergy Rx alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

MadeMed Synergy Rx
PCOS & hormonal suitability8280
MadeMed
Synergy
Clinical oversight & labs8082
MadeMed
Synergy
Price transparency9558
MadeMed
Synergy
Nationwide access8474
MadeMed
Synergy
Ongoing support8090
MadeMed
Synergy
Cancellation fairness8470
MadeMed
Synergy

Price, access & features

DetailMadeMedSynergy Rx
Luna Fit Score84/100 · B76/100 · C
Overall rank#7#44
Semaglutide$239/mo quarterly (from $199/mo on 6 months)From $199/mo
Tirzepatide$399/mo quarterly (from $369/mo on 6 months)From $349/mo
Coverage40 statesNot disclosed
Brand-name accessCompounded onlyYes
Oral / sublingualYesInjection only

MadeMed

Ranked #7 · Grade B

What we like

  • One price at every dose, published dose by dose — semaglutide $239/mo from 0.25mg to 2.4mg, tirzepatide $399/mo from 2.5mg to 15mg
  • LegitScript verified, with board-certified physician review and US compounding pharmacies
  • Oral semaglutide and oral tirzepatide are both offered alongside the injections

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • 40 states rather than nationwide — check yours before you start
  • Tirzepatide is among the pricier entries in this ranking at $399/mo quarterly

Synergy Rx

Ranked #44 · Grade C

What we like

  • Will prescribe FDA-approved brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate — rare in this ranking
  • Unlimited appointments, messaging and 24/7 access to a dedicated clinical team
  • FSA and HSA eligible

The caveats

  • Publishes no GLP-1 price on its own site — the longevity line is priced openly, the medication this page is about is not
  • At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither MadeMed nor Synergy Rx is only worth comparing with the other. MadeMed is also written up against CoreAge Rx, 9 points apart on the Luna Fit Score — see MadeMed vs CoreAge Rx for women. Synergy Rx is also written up against CoreAge Rx, 17 points apart — see Synergy Rx against CoreAge Rx, factor by factor.

Or browse the full comparison hub.