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Head-to-head for women
Sesame Care vs Synergy Rx
Sesame Care and Synergy Rx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Sesame Care
Higher scoreRanked #5 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareSynergy Rx
Ranked #44 for women · Grade C
Luna Fit
Best for: Women who specifically want a brand-name path and unlimited clinical contact, and who are prepared to get pricing by enquiry.
Visit Synergy RxThe verdict for women
Sesame Care edges out Synergy Rx on the Luna Fit Score, 85 to 76 (B vs C). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.
Synergy Rx is still a genuine option — one of the few programs here that will prescribe brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited 24/7 access to its clinical team — though you will not find a GLP-1 price anywhere on its site. Weigh the six women's-health factors below against your own priorities; our Synergy Rx write-up for women goes through each of them, and if neither of these two is the one, the Synergy Rx alternatives, scored on the same six factors widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame Care | Synergy Rx |
|---|---|---|
| Luna Fit Score | 85/100 · B | 76/100 · C |
| Overall rank | #5 | #44 |
| Semaglutide | Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) | From $199/mo |
| Tirzepatide | Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days | From $349/mo |
| Coverage | Nationwide marketplace | Not disclosed |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Injection only |
Luna Fit
Sesame Care
Ranked #5 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Luna Fit
Synergy Rx
Ranked #44 · Grade C
What we like
- Will prescribe FDA-approved brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate — rare in this ranking
- Unlimited appointments, messaging and 24/7 access to a dedicated clinical team
- FSA and HSA eligible
The caveats
- Publishes no GLP-1 price on its own site — the longevity line is priced openly, the medication this page is about is not
- At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Sesame Care nor Synergy Rx is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. Synergy Rx is also written up against CoreAge Rx, 17 points apart — see Synergy Rx against CoreAge Rx, factor by factor.
- Sesame Care vs CoreAge Rx
- Sesame Care vs Enhance MD
- Sesame Care vs Eden
- Synergy Rx vs yourEra
- Synergy Rx vs HealthRX
- Synergy Rx vs MadeMed
Or browse the full comparison hub.