Head-to-head for women
Sesame Care vs ShedRx
Sesame Care and ShedRx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Sesame Care
Higher scoreRanked #4 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareShedRx
Ranked #9 for women · Grade B
Luna Fit
Best for: Women who want an oral or sublingual option rather than weekly injections, at competitive tirzepatide pricing.
Visit ShedRxThe verdict for women
Sesame Care edges out ShedRx on the Luna Fit Score, 85 to 83 (B vs B). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.
ShedRx is still a genuine option — a weight-focused program that also offers an oral/sublingual route — a genuine relief for the needle-averse and for anyone easing in gradually. Weigh the six women's-health factors below against your own priorities; the ShedRx scorecard goes through each of them, and if neither of these two is the one, what women pick instead of ShedRx widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame Care | ShedRx |
|---|---|---|
| Luna Fit Score | 85/100 · B | 83/100 · B |
| Overall rank | #4 | #9 |
| Semaglutide | Care $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg | $199/mo |
| Tirzepatide | Care $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) | $299/mo |
| Coverage | Nationwide marketplace | Not disclosed |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Yes |
Luna Fit
Sesame Care
Ranked #4 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Luna Fit
ShedRx
Ranked #9 · Grade B
What we like
- Offers oral/sublingual forms — a real alternative to weekly shots
- Competitive tirzepatide pricing
- Weight-focused program with titration support
The caveats
- States-served not disclosed
- Compounded only
- Hormonal/PCOS framing is general, not specialized
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Sesame Care nor ShedRx is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. ShedRx is also written up against CoreAge Rx, 10 points apart — see the ShedRx–CoreAge Rx head-to-head.
- Sesame Care vs CoreAge Rx
- Sesame Care vs Enhance MD
- Sesame Care vs yourEra
- ShedRx vs HealthRX
- ShedRx vs MadeMed
- ShedRx vs Trimi
Or browse the full comparison hub.