Head-to-head for women
Enhance MD vs Sesame Care
Enhance MD and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Enhance MD
Higher scoreRanked #2 for women · Grade A−
Luna Fit
Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Visit Enhance MDSesame Care
Ranked #5 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareThe verdict for women
Enhance MD edges out Sesame Care on the Luna Fit Score, 92 to 85 (A− vs B). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Sesame Care is still a genuine option — an established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency. Weigh the six women's-health factors below against your own priorities.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Enhance MD | Sesame Care |
|---|---|---|
| Luna Fit Score | 92/100 · A− | 85/100 · B |
| Overall rank | #2 | #5 |
| Semaglutide | $212/mo | From $149/mo (brand Wegovy pill) |
| Tirzepatide | $280/mo | Brand Zepbound (price varies) |
| Coverage | All 50 states | Nationwide marketplace |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Luna Fit
Enhance MD
Ranked #2 · Grade A−
What we like
- Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
- Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
- Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- No brand-name path and no oral or sublingual route for the needle-averse
- Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start
Luna Fit
Sesame Care
Ranked #5 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score; affiliate partners carry a capped 6-point edge in list order, never in the score itself. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing Enhance MD and Sesame Care against other providers we review for women.
- Enhance MD vs CoreAge Rx
- Enhance MD vs Gala Health
- Enhance MD vs yourEra
- Sesame Care vs HealthRX
- Sesame Care vs Strut Health
- Sesame Care vs MadeMed
Or browse the full comparison hub.