Head-to-head for women
Sesame Care vs SkinnyRx
Sesame Care and SkinnyRx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Sesame Care
Higher scoreRanked #4 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareSkinnyRx
Ranked #51 for women · Grade C
Luna Fit
Best for: Readers treating insulin resistance who want the dual GIP/GLP-1 molecule without a weekly injection, and who will open the plan selector and read the month-to-month rate rather than the advertised one.
FDA warning letterFebruary 2026Read it ↗Visit SkinnyRxThe verdict for women
Sesame Care edges out SkinnyRx on the Luna Fit Score, 85 to 71 (B vs C). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.
SkinnyRx is still a genuine option — the rare program that compounds tirzepatide as a dissolving tablet as well as an injection — genuinely useful if the needle is what is stopping you — sold behind a four-rung commitment ladder whose cheapest rung is the only price the site ever shows you. Weigh the six women's-health factors below against your own priorities; the SkinnyRx scorecard goes through each of them, and if neither of these two is the one, our ranked shortlist of SkinnyRx alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame Care | SkinnyRx |
|---|---|---|
| Luna Fit Score | 85/100 · B | 71/100 · C |
| Overall rank | #4 | #51 |
| Semaglutide | From $149/mo (brand Wegovy pill) | $349/mo month-to-month (from $199/mo on a 12-month plan) — the site displays only the 12-month rate |
| Tirzepatide | Brand Zepbound (price varies) | $399/mo month-to-month, injectable or dissolving tablet (from $299/mo on a 12-month plan) — the site displays only the 12-month rate |
| Coverage | Nationwide marketplace | No state list published; the offer terms report no state restrictions |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Yes |
Luna Fit
Sesame Care
Ranked #4 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Luna Fit
SkinnyRx
Ranked #51 · Grade C
What we like
- A compounded tirzepatide TABLET — a dissolving sublingual route for the dual GIP/GLP-1 molecule, priced identically to the injection at every rung, which is close to unique in this ranking
- Both molecules across three routes — injection, sublingual and daily tablet — so needle aversion never means changing provider or dropping back to the single-pathway drug
- Lower-dose "microdose" lines for both molecules are sold as their own products with their own published ladders, rather than being quoted at the full-dose price
The caveats
- Carries an active FDA warning letter issued in February 2026 (see the notice on this page for FDA's own record)
- Every price the site advertises is the TWELVE-MONTH rung: its own headline reads "Starting at $299/mo" while the month-to-month tirzepatide rate is $399 and the renewal price in its code is literally 399 — semaglutide is the same shape at $199 advertised against $349 month-to-month
- The commitment is not named beside the number anywhere in the marketing copy, and the prepay rung is also what its schema.org product markup publishes as the price — so search engines and AI assistants are given the twelve-month rate as though it were the monthly one
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Sesame Care nor SkinnyRx is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. SkinnyRx is also written up against CoreAge Rx, 22 points apart — see the SkinnyRx–CoreAge Rx head-to-head.
- Sesame Care vs CoreAge Rx
- Sesame Care vs Enhance MD
- Sesame Care vs yourEra
- SkinnyRx vs HealthRX
- SkinnyRx vs MadeMed
- SkinnyRx vs Trimi
Or browse the full comparison hub.