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Head-to-head for women

Sesame Care vs Telos Rx

Sesame Care and Telos Rx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Sesame Care

Higher score

Ranked #4 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care
vs

Telos Rx

Ranked #11 for women · Grade B

Best for: Women who want GLP-1 care under the same roof as bioidentical HRT and needle-free options, from a LegitScript-certified compounder, and who are comfortable vetting a broad menu themselves.

Visit Telos Rx

The verdict for women

Higher Luna Fit Score: Sesame Care

Sesame Care edges out Telos Rx on the Luna Fit Score, 85 to 83 (B vs B). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.

Telos Rx is still a genuine option — one of the deepest catalogs we log for a woman managing metabolism and hormones together — semaglutide and tirzepatide in oral, microdosed, and injectable forms, plus bioidentical HRT and a long peptide menu, from a LegitScript-certified, HIPAA-compliant compounder. Weigh the six women's-health factors below against your own priorities; our Telos Rx write-up for women goes through each of them, and if neither of these two is the one, the full field we rank against Telos Rx widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Sesame Care Telos Rx
PCOS & hormonal suitability8488
Sesame
Telos
Clinical oversight & labs8883
Sesame
Telos
Price transparency8080
Sesame
Telos
Nationwide access9280
Sesame
Telos
Ongoing support8285
Sesame
Telos
Cancellation fairness8582
Sesame
Telos

Price, access & features

DetailSesame CareTelos Rx
Luna Fit Score85/100 · B83/100 · B
Overall rank#4#11
SemaglutideCare $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg$99/mo injectable — the $49 headline is only the FIRST month of the 12-month prepaid ORAL plan, which renews at $129/mo billed every 48 weeks
TirzepatideCare $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg)$139/mo injectable · $129/mo oral · $116/mo microdosed (microdosing is tirzepatide, not semaglutide)
CoverageNationwide marketplaceNot publicly listed
Brand-name accessYesCompounded only
Oral / sublingualYesYes

Sesame Care

Ranked #4 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Telos Rx

Ranked #11 · Grade B

What we like

  • Deep catalog that includes bioidentical HRT — genuinely relevant for women managing metabolism and hormones at once
  • Needle-free and oral GLP-1 options, plus microdosed lanes for a gradual on-ramp
  • LegitScript-certified and HIPAA-compliant, with HSA/FSA accepted and free shipping

The caveats

  • Everything is compounded — not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • Pricing is opaque outside GLP-1, and the low rates hinge on annual lock-in
  • No named clinicians and thin public reviews, so the oversight signal is harder to verify

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Sesame Care nor Telos Rx is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. Telos Rx is also written up against CoreAge Rx, 10 points apart — see Telos Rx against CoreAge Rx, factor by factor.

Or browse the full comparison hub.