Head-to-head for women
Sesame Care vs Trimi
Sesame Care and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Sesame Care
Higher scoreRanked #4 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareTrimi
Ranked #8 for women · Grade B
Luna Fit
Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.
Visit TrimiThe verdict for women
Sesame Care edges out Trimi on the Luna Fit Score, 85 to 84 (B vs B). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.
Trimi is still a genuine option — among the lowest verified prices we log — compounded semaglutide and tirzepatide on a single membership, shipped nationwide. A budget-first on-ramp for women who want tirzepatide access without paying a premium. Weigh the six women's-health factors below against your own priorities; what we found reviewing Trimi goes through each of them, and if neither of these two is the one, what women pick instead of Trimi widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame Care | Trimi |
|---|---|---|
| Luna Fit Score | 85/100 · B | 84/100 · B |
| Overall rank | #4 | #8 |
| Semaglutide | From $149/mo (brand Wegovy pill) | $129/mo |
| Tirzepatide | Brand Zepbound (price varies) | $229/mo |
| Coverage | Nationwide marketplace | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Injection only |
Luna Fit
Sesame Care
Ranked #4 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Luna Fit
Trimi
Ranked #8 · Grade B
What we like
- Among the lowest published prices we track on both semaglutide and tirzepatide
- Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
- Nationwide across all 50 states with free shipping
The caveats
- Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
- Injectable only — no oral or sublingual route for the needle-averse
- Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Sesame Care nor Trimi is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.
- Sesame Care vs CoreAge Rx
- Sesame Care vs Enhance MD
- Sesame Care vs yourEra
- Trimi vs HealthRX
- Trimi vs Strut Health
- Trimi vs MadeMed
Or browse the full comparison hub.