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Head-to-head for women
Sesame Care vs Tyde Wellness
Sesame Care and Tyde Wellness both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Sesame Care
Ranked #5 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareTyde Wellness
Higher scoreRanked #23 for women · Grade B
Luna Fit
Best for: Women who want an oral or sublingual alternative to weekly shots from a LegitScript-accredited, nationwide provider.
Visit Tyde WellnessThe verdict for women
Tyde Wellness edges out Sesame Care on the Luna Fit Score, 86 to 85 (B vs B). Women who want an oral or sublingual alternative to weekly shots from a LegitScript-accredited, nationwide provider. The reasoning behind that number is in our Tyde Wellness write-up for women.
Sesame Care is still a genuine option — an established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency. Weigh the six women's-health factors below against your own priorities; the Sesame Care scorecard goes through each of them, and if neither of these two is the one, the Sesame Care alternatives, scored on the same six factors widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame Care | Tyde Wellness |
|---|---|---|
| Luna Fit Score | 85/100 · B | 86/100 · B |
| Overall rank | #5 | #23 |
| Semaglutide | Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) | $149/mo |
| Tirzepatide | Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days | $249/mo |
| Coverage | Nationwide marketplace | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Yes |
Luna Fit
Sesame Care
Ranked #5 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Luna Fit
Tyde Wellness
Ranked #23 · Grade B
What we like
- Offers an oral/sublingual route as well as injections — a genuine option for the needle-averse
- LegitScript-accredited and available in all 50 states
- Both molecules disclosed, with tirzepatide for insulin-resistant PCOS
The caveats
- Mid-to-higher tirzepatide pricing at $249
- No FDA-approved brand access; general program rather than hormone-specialized
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Sesame Care nor Tyde Wellness is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. Tyde Wellness is also written up against Vaylen, 1 point apart — see the Tyde Wellness–Vaylen head-to-head.
- Sesame Care vs CoreAge Rx
- Sesame Care vs Enhance MD
- Sesame Care vs Eden
- Tyde Wellness vs yourEra
- Tyde Wellness vs HealthRX
- Tyde Wellness vs MadeMed
Or browse the full comparison hub.