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Head-to-head for women

Sesame Care vs Tyde Wellness

Sesame Care and Tyde Wellness both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Sesame Care

Higher score

Ranked #8 for women · Grade B+

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

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vs

Tyde Wellness

Ranked #11 for women · Grade B

Best for: Women who want an oral or sublingual alternative to weekly shots from a LegitScript-accredited, nationwide provider.

Visit Tyde Wellness

The verdict for women

Higher Luna Fit Score: Sesame Care

Sesame Care edges out Tyde Wellness on the Luna Fit Score, 87 to 86 (B+ vs B). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Tyde Wellness is still a genuine option — an accredited, all-50-states program that offers an oral option alongside injections — real flexibility for a woman easing into GLP-1 care. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Sesame Care Tyde Wellness
PCOS & hormonal suitability8485
Sesame
Tyde
Clinical oversight & labs8887
Sesame
Tyde
Price transparency8084
Sesame
Tyde
Nationwide access9295
Sesame
Tyde
Ongoing support8284
Sesame
Tyde
Cancellation fairness8583
Sesame
Tyde

Price, access & features

DetailSesame CareTyde Wellness
Luna Fit Score87/100 · B+86/100 · B
Overall rank#8#11
SemaglutideFrom $149/mo (brand Wegovy pill)$149/mo
TirzepatideBrand Zepbound (price varies)$249/mo
CoverageNationwide marketplaceAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualYesYes

Sesame Care

Ranked #8 · Grade B+

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Tyde Wellness

Ranked #11 · Grade B

What we like

  • Offers an oral/sublingual route as well as injections — a genuine option for the needle-averse
  • LegitScript-accredited and available in all 50 states
  • Both molecules disclosed, with tirzepatide for insulin-resistant PCOS

The caveats

  • Mid-to-higher tirzepatide pricing at $249
  • No FDA-approved brand access; general program rather than hormone-specialized

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing Sesame Care and Tyde Wellness against other providers we review for women.

Or browse the full comparison hub.