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Head-to-head for women

Trimi vs Sesame Care

Trimi and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Trimi

Ranked #9 for women · Grade B

Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.

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vs

Sesame Care

Higher score

Ranked #5 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

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The verdict for women

Higher Luna Fit Score: Sesame Care

Sesame Care edges out Trimi on the Luna Fit Score, 85 to 84 (B vs B). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Trimi is still a genuine option — among the lowest verified prices we log — compounded semaglutide and tirzepatide on a single membership, shipped nationwide. A budget-first on-ramp for women who want tirzepatide access without paying a premium. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Trimi Sesame Care
PCOS & hormonal suitability8484
Trimi
Sesame
Clinical oversight & labs7888
Trimi
Sesame
Price transparency9280
Trimi
Sesame
Nationwide access9092
Trimi
Sesame
Ongoing support8082
Trimi
Sesame
Cancellation fairness8085
Trimi
Sesame

Price, access & features

DetailTrimiSesame Care
Luna Fit Score84/100 · B85/100 · B
Overall rank#9#5
Semaglutide$129/moFrom $149/mo (brand Wegovy pill)
Tirzepatide$229/moBrand Zepbound (price varies)
CoverageAll 50 statesNationwide marketplace
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes

Trimi

Ranked #9 · Grade B

What we like

  • Among the lowest published prices we track on both semaglutide and tirzepatide
  • Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
  • Nationwide across all 50 states with free shipping

The caveats

  • Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
  • Injectable only — no oral or sublingual route for the needle-averse
  • Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner

Sesame Care

Ranked #5 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score; affiliate partners carry a capped 6-point edge in list order, never in the score itself. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing Trimi and Sesame Care against other providers we review for women.

Or browse the full comparison hub.