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Head-to-head for women

Sesame Care vs yourEra

Sesame Care and yourEra both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Sesame Care

Ranked #5 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care
vs

yourEra

Higher score

Ranked #4 for women · Grade B

Best for: Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account.

Visit yourEra

The verdict for women

Higher Luna Fit Score: yourEra

yourEra edges out Sesame Care on the Luna Fit Score, 86 to 85 (B vs B). Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account. The reasoning behind that number is in our full yourEra review.

Sesame Care is still a genuine option — an established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency. Weigh the six women's-health factors below against your own priorities; the Sesame Care scorecard goes through each of them, and if neither of these two is the one, the Sesame Care alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Sesame Care yourEra
PCOS & hormonal suitability8484
Sesame
yourEra
Clinical oversight & labs8885
Sesame
yourEra
Price transparency8088
Sesame
yourEra
Nationwide access9290
Sesame
yourEra
Ongoing support8286
Sesame
yourEra
Cancellation fairness8582
Sesame
yourEra

Price, access & features

DetailSesame CareyourEra
Luna Fit Score85/100 · B86/100 · B
Overall rank#5#4
SemaglutideBrand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)$199/mo
TirzepatideBrand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days$299/mo
CoverageNationwide marketplaceAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only

Sesame Care

Ranked #5 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

yourEra

Ranked #4 · Grade B

What we like

  • Publicly listed pricing on both molecules — semaglutide from $199/mo and tirzepatide from $299/mo — while many compounders hide price behind a quiz
  • Fuller menu beyond GLP-1: NAD+ and microdosing protocols, plus an optional membership adding 1:1 coaching, a nutritionist, and an at-home lab draw
  • Markets a 50-state licensed-clinician network, no insurance required, with HSA/FSA accepted

The caveats

  • Compounded semaglutide and tirzepatide are not FDA-approved the way brand Wegovy, Ozempic, or Zepbound are, and compounding access can tighten as brand shortages resolve
  • Mid-market pricing that sits above the cheapest compounders (roughly $99–$150)
  • Injectable only — no oral route and no brand-name lane

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Sesame Care nor yourEra is only worth comparing with the other. Sesame Care is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see Sesame Care against CoreAge Rx, factor by factor. yourEra is also written up against CoreAge Rx, 7 points apart — see how yourEra and CoreAge Rx compare on the Luna Fit Score.

Or browse the full comparison hub.