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Head-to-head for women

Alloy vs Enhance MD

Alloy and Enhance MD both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Alloy

Ranked #41 for women · Grade B−

Best for: Women in perimenopause or menopause who want the clinician managing their weight to be the same one who understands their hormones — and who can absorb a membership fee on top of the drug price.

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vs

Enhance MD

Higher score

Ranked #2 for women · Grade A−

Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

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The verdict for women

Higher Luna Fit Score: Enhance MD

Enhance MD edges out Alloy on the Luna Fit Score, 92 to 82 (A− vs B−). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.

Alloy is still a genuine option — the only program on this board built for midlife first: your prescriber is a Menopause Society–certified physician, and weight care sits alongside a full hormone-therapy line rather than being sold in isolation. Weigh the six women's-health factors below against your own priorities; what we found reviewing Alloy goes through each of them, and if neither of these two is the one, the Alloy alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Alloy Enhance MD
PCOS & hormonal suitability8892
Alloy
Enhance
Clinical oversight & labs8494
Alloy
Enhance
Price transparency7894
Alloy
Enhance
Nationwide access7095
Alloy
Enhance
Ongoing support9388
Alloy
Enhance
Cancellation fairness7685
Alloy
Enhance

Price, access & features

DetailAlloyEnhance MD
Luna Fit Score82/100 · B−92/100 · A−
Overall rank#41#2
SemaglutideFrom $169/mo all-in ($70 medication + $99 membership)$212/mo
TirzepatideFrom $199/mo all-in ($100 medication + $99 membership)$280/mo
CoverageNot disclosed; compounded excluded in 6 states and DCAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only

Alloy

Ranked #41 · Grade B−

What we like

  • Prescribers hold the Menopause Society Certified Practitioner credential — the only board entry where that is true of named clinicians
  • The widest formulary here: compounded semaglutide, tirzepatide and liraglutide, plus brand Wegovy, Zepbound and the Wegovy and Foundayo pills
  • Oral routes are FDA-approved brand pills, not a compounded workaround, for women who will not inject

The caveats

  • The $99/mo membership is charged on top of every medication price, so the headline figure is not what you pay
  • Every price is quoted 'starting at' with no published dose table — the rate can move as you titrate
  • Compounded medication is unavailable in six states and DC, and the overall coverage footprint is not published anywhere on the site

Enhance MD

Ranked #2 · Grade A−

What we like

  • Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
  • Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
  • Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • No brand-name path and no oral or sublingual route for the needle-averse
  • Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Alloy nor Enhance MD is only worth comparing with the other. Alloy is also written up against CoreAge Rx, 11 points apart on the Luna Fit Score — see Alloy vs CoreAge Rx for women. Enhance MD is also written up against CoreAge Rx, 1 point apart — see the Enhance MD–CoreAge Rx head-to-head.

Or browse the full comparison hub.