Head-to-head for women
BetterMe Rx vs Sesame Care
BetterMe Rx and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
BetterMe Rx
Higher scoreRanked #30 for women · Grade B
Luna Fit
Best for: Women who want lifestyle and behavior support alongside medication, plus an oral option, from an accredited nationwide provider.
Visit BetterMe RxSesame Care
Ranked #4 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareThe verdict for women
BetterMe Rx edges out Sesame Care on the Luna Fit Score, 86 to 85 (B vs B). Women who want lifestyle and behavior support alongside medication, plus an oral option, from an accredited nationwide provider. The reasoning behind that number is in what we found reviewing BetterMe Rx.
Sesame Care is still a genuine option — an established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency. Weigh the six women's-health factors below against your own priorities; the Sesame Care scorecard goes through each of them, and if neither of these two is the one, the Sesame Care alternatives, scored on the same six factors widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | BetterMe Rx | Sesame Care |
|---|---|---|
| Luna Fit Score | 86/100 · B | 85/100 · B |
| Overall rank | #30 | #4 |
| Semaglutide | $199/mo | Care $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg |
| Tirzepatide | $299/mo | Care $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) |
| Coverage | All 50 states | Nationwide marketplace |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Yes |
Luna Fit
BetterMe Rx
Ranked #30 · Grade B
What we like
- Behavior-change heritage — useful for the lifestyle levers in PCOS
- Offers an oral/sublingual route and both molecules
- LegitScript-accredited, nationwide
The caveats
- Mid-market pricing, not the cheapest
- Hormone/PCOS framing is general, not specialized
Luna Fit
Sesame Care
Ranked #4 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither BetterMe Rx nor Sesame Care is only worth comparing with the other. BetterMe Rx is also written up against CoreAge Rx, 7 points apart on the Luna Fit Score — see BetterMe Rx vs CoreAge Rx for women. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.
- BetterMe Rx vs CoreAge Rx
- BetterMe Rx vs Enhance MD
- BetterMe Rx vs yourEra
- Sesame Care vs HealthRX
- Sesame Care vs MadeMed
- Sesame Care vs Trimi
Or browse the full comparison hub.