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Head-to-head for women

HealthRX vs Sesame Care

HealthRX and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

HealthRX

Ranked #6 for women · Grade B

Best for: Women who want a LegitScript-certified, physician-supervised program with both molecules, an oral-tablet route as well as injections, and transparent flat pricing with no insurance to navigate.

Visit HealthRX
vs

Sesame Care

Ranked #5 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care

The verdict for women

HealthRX and Sesame Care tie on the Luna Fit Score at 85/100 apiece, so neither runs away with it. The right pick comes down to the factors that matter most to you — compare them below, or read the HealthRX scorecard and the Sesame Care scorecard in full. If the answer is still neither, the alternatives to HealthRX we rank for women widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

HealthRX Sesame Care
PCOS & hormonal suitability8684
HealthRX
Sesame
Clinical oversight & labs8788
HealthRX
Sesame
Price transparency8680
HealthRX
Sesame
Nationwide access8092
HealthRX
Sesame
Ongoing support8582
HealthRX
Sesame
Cancellation fairness8485
HealthRX
Sesame

Price, access & features

DetailHealthRXSesame Care
Luna Fit Score85/100 · B85/100 · B
Overall rank#6#5
Semaglutide$190/mo month-to-month ($99 first month, renews at $165) · $99/mo on a 12-month prepay ($1,188)Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)
Tirzepatide$239/mo month-to-month ($149 first month, renews at $214) · $179/mo on a 12-month prepay ($2,148)Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days
CoverageNot publicly listedNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes

HealthRX

Ranked #6 · Grade B

What we like

  • LegitScript-certified (a meaningful third-party trust signal) with physician-supervised care, not a prescription-only handoff
  • Both molecules plus a rare oral GLP-1 tablet — real optionality for the needle-averse and for insulin-resistant PCOS
  • Transparent, no-insurance flat pricing — injectable GLP-1 around $189/mo, oral tablet around $239/mo, GLP+GIP around $349/mo

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • Some tiers are company-stated and the public site is thin, so a few figures can't be verified live
  • Brand-name tiers are pass-through and expensive — brand Ozempic runs about $1,299/mo

Sesame Care

Ranked #5 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither HealthRX nor Sesame Care is only worth comparing with the other. HealthRX is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see the HealthRX–CoreAge Rx head-to-head. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.

Or browse the full comparison hub.