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Head-to-head for women
Edessa vs He & She MD
Edessa and He & She MD both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Edessa
Ranked #74 for women · Grade C
Luna Fit
Best for: A woman prepared to prepay six months, or one willing to click past the front page to the table carrying the real monthly rate.
Visit EdessaHe & She MD
Higher scoreRanked #25 for women · Grade B−
Luna Fit
Best for: Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length.
Visit He & She MDThe verdict for women
He & She MD edges out Edessa on the Luna Fit Score, 80 to 69 (B− vs C). Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length. The reasoning behind that number is in the He & She MD scorecard.
Edessa is still a genuine option — clean three-rung tables one click in, behind a front page whose three cards all quote six-month rungs and whose cheapest belongs to a different drug. Weigh the six women's-health factors below against your own priorities; what we found reviewing Edessa goes through each of them, and if neither of these two is the one, what women pick instead of Edessa widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Edessa | He & She MD |
|---|---|---|
| Luna Fit Score | 69/100 · C | 80/100 · B− |
| Overall rank | #74 | #25 |
| Semaglutide | $179/mo month-to-month for the injection ($135 only on a six-month prepay) | $199/mo month-to-month ($1,188 once for a year is the $99/mo on the banners) |
| Tirzepatide | $239/mo month-to-month ($209 only on a six-month prepay) | $299/mo month-to-month ($1,908 committed for the year) |
| Coverage | Not publicly listed | Every US state except Louisiana for GLP-1s; hormone and longevity lines ship nationwide |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Luna Fit
Edessa
Ranked #74 · Grade C
What we like
- Each product page carries a plain three-rung table, so the commitment behind every figure is visible
- "Same price, every dose" is printed on each product page
- Names its operating entity and a full street address in Las Vegas, Nevada
The caveats
- The front page leads with "Start for just $135", a six-month prepay on the semaglutide injection; month-to-month tirzepatide is $239
- All three front-page cards quote the six-month rung, so the real monthly rates appear only after a click
- Its Terms give two corporate forms for the same company in one clause — "Edessa Group, LLC, a Nevada corporation"
Luna Fit
He & She MD
Ranked #25 · Grade B−
What we like
- Sells estradiol (patch, gel and pill) and progesterone alongside its GLP-1s, so the menopause and metabolic sides run through one intake
- Prices four commitment terms per GLP-1 molecule in public, with the amount actually charged printed beside each
- Names the dispensing pharmacy in full — F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield OH 45014, with a phone number
The caveats
- The menopause line is the one place it stops publishing terms: estradiol patch, gel and pill and the progesterone pill all show "Starting at $125/month" with no term table at all, while seven other product pages carry a full four-rung ladder
- Every advertised GLP-1 figure is the twelve-month rung — the "$99/month" on the banners requires $1,188 paid once, and the rate you can stop after a month is $199
- Its FAQ says the pharmacy it names is licensed in 44 states and cannot dispense sterile compounds; a weekly GLP-1 injection is a sterile compound, and a second pharmacy is named in the same answer without saying which fills what
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Edessa nor He & She MD is only worth comparing with the other. Edessa is also written up against CoreAge Rx, 24 points apart on the Luna Fit Score — see how Edessa and CoreAge Rx compare on the Luna Fit Score. He & She MD is also written up against CoreAge Rx, 13 points apart — see He & She MD against CoreAge Rx, factor by factor.
- Edessa vs CoreAge Rx
- Edessa vs Enhance MD
- Edessa vs Eden
- He & She MD vs yourEra
- He & She MD vs Sesame Care
- He & She MD vs HealthRX
Or browse the full comparison hub.