Head-to-head for women
He & She MD vs yourEra
He & She MD and yourEra both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
He & She MD
Ranked #25 for women · Grade B−
Luna Fit
Best for: Women who want the GLP-1 and the hormone conversation handled by one clinician rather than split across two providers, and who will read the asterisk before choosing a plan length.
Visit He & She MDyourEra
Higher scoreRanked #3 for women · Grade B
Luna Fit
Best for: Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account.
Visit yourEraThe verdict for women
yourEra edges out He & She MD on the Luna Fit Score, 86 to 80 (B vs B−). Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account. The reasoning behind that number is in our full yourEra review.
He & She MD is still a genuine option — the one desk here that also sells the menopause side — estradiol as a patch, a gel or a pill plus progesterone — under the same intake as its GLP-1s, and the only line on the site whose price has no term table behind it. Weigh the six women's-health factors below against your own priorities; the He & She MD scorecard goes through each of them, and if neither of these two is the one, our ranked shortlist of He & She MD alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | He & She MD | yourEra |
|---|---|---|
| Luna Fit Score | 80/100 · B− | 86/100 · B |
| Overall rank | #25 | #3 |
| Semaglutide | $199/mo month-to-month ($1,188 once for a year is the $99/mo on the banners) | $199/mo |
| Tirzepatide | $299/mo month-to-month ($1,908 committed for the year) | $299/mo |
| Coverage | Every US state except Louisiana for GLP-1s; hormone and longevity lines ship nationwide | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Luna Fit
He & She MD
Ranked #25 · Grade B−
What we like
- Sells estradiol (patch, gel and pill) and progesterone alongside its GLP-1s, so the menopause and metabolic sides run through one intake
- Prices four commitment terms per GLP-1 molecule in public, with the amount actually charged printed beside each
- Names the dispensing pharmacy in full — F&F Pharmacies Inc, doing business as Jungle Jim's Pharmacy, 5484 Dixie Highway, Fairfield OH 45014, with a phone number
The caveats
- ⚠ The menopause line is the one place it stops publishing terms: estradiol patch, gel and pill and the progesterone pill all show "Starting at $125/month" with no term table at all, while seven other product pages carry a full four-rung ladder
- ⚠ Every advertised GLP-1 figure is the twelve-month rung — the "$99/month" on the banners requires $1,188 paid once, and the rate you can stop after a month is $199
- Its FAQ says the pharmacy it names is licensed in 44 states and cannot dispense sterile compounds; a weekly GLP-1 injection is a sterile compound, and a second pharmacy is named in the same answer without saying which fills what
Luna Fit
yourEra
Ranked #3 · Grade B
What we like
- Publicly listed pricing on both molecules — semaglutide from $199/mo and tirzepatide from $299/mo — while many compounders hide price behind a quiz
- Fuller menu beyond GLP-1: NAD+ and microdosing protocols, plus an optional membership adding 1:1 coaching, a nutritionist, and an at-home lab draw
- Markets a 50-state licensed-clinician network, no insurance required, with HSA/FSA accepted
The caveats
- Compounded semaglutide and tirzepatide are not FDA-approved the way brand Wegovy, Ozempic, or Zepbound are, and compounding access can tighten as brand shortages resolve
- Mid-market pricing that sits above the cheapest compounders (roughly $99–$150)
- Injectable only — no oral route and no brand-name lane
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither He & She MD nor yourEra is only worth comparing with the other. He & She MD is also written up against CoreAge Rx, 13 points apart on the Luna Fit Score — see He & She MD against CoreAge Rx, factor by factor. yourEra is also written up against CoreAge Rx, 7 points apart — see how yourEra and CoreAge Rx compare on the Luna Fit Score.
- He & She MD vs CoreAge Rx
- He & She MD vs Enhance MD
- He & She MD vs Sesame Care
- yourEra vs HealthRX
- yourEra vs MadeMed
- yourEra vs Trimi
Or browse the full comparison hub.