Head-to-head for women
Enhance MD vs Good Girl Rx
Enhance MD and Good Girl Rx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Enhance MD
Higher scoreRanked #2 for women · Grade A−
Luna Fit
Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Visit Enhance MDGood Girl Rx
Ranked #47 for women · Grade C
Luna Fit
Best for: Women who want injectable, microdose, sublingual and brand-name routes on one account and are reading the safety page as carefully as the price page.
Visit Good Girl RxThe verdict for women
Enhance MD edges out Good Girl Rx on the Luna Fit Score, 92 to 76 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.
Good Girl Rx is still a genuine option — a women-first brand with the clearest contraception guidance we found anywhere on this board — and an FDA warning letter for how it labelled its compounded products, which is the reason it does not rank higher. Weigh the six women's-health factors below against your own priorities; what we found reviewing Good Girl Rx goes through each of them, and if neither of these two is the one, our ranked shortlist of Good Girl Rx alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Enhance MD | Good Girl Rx |
|---|---|---|
| Luna Fit Score | 92/100 · A− | 76/100 · C |
| Overall rank | #2 | #47 |
| Semaglutide | $212/mo | $179/mo month-to-month (from $134/mo on a 12-month prepay) |
| Tirzepatide | $280/mo | $329/mo month-to-month (from $235/mo on a 12-month prepay) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Luna Fit
Enhance MD
Ranked #2 · Grade A−
What we like
- Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
- Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
- Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- No brand-name path and no oral or sublingual route for the needle-averse
- Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start
Luna Fit
Good Girl Rx
Ranked #47 · Grade C
What we like
- The best contraception guidance on the board: a two-month semaglutide washout before a planned pregnancy, and a warning that tirzepatide can blunt oral contraceptives for four weeks after starting AND after every dose increase
- Four routes for each molecule — injection, microdose, sublingual dissolving tablet and brand — so a switch does not mean changing provider
- Publishes a full per-plan price table for every product rather than one headline figure
The caveats
- FDA warning letter MARCS-CMS 721449, dated 20 February 2026, to Good Girl LLC dba GoodGirlRX: the FDA found its product labelling suggested the company itself compounded the drugs, and objected to marketing claims made about compounded products
- Every advertised 'from' price is a 12-month plan paid upfront, and dispensed prescriptions are final sale — a year's commitment with no way back
- The microdose one-month rate is HIGHER than the standard injection one-month rate; the microdose discount exists only on prepay
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Enhance MD nor Good Girl Rx is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. Good Girl Rx is also written up against CoreAge Rx, 17 points apart — see how Good Girl Rx and CoreAge Rx compare on the Luna Fit Score.
- Enhance MD vs CoreAge Rx
- Enhance MD vs yourEra
- Enhance MD vs Sesame Care
- Good Girl Rx vs HealthRX
- Good Girl Rx vs Strut Health
- Good Girl Rx vs MadeMed
Or browse the full comparison hub.