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Head-to-head for women

Good Girl Rx vs Sesame Care

Good Girl Rx and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Good Girl Rx

Ranked #60 for women · Grade C

Best for: Women who want injectable, microdose, sublingual and brand-name routes on one account and are reading the safety page as carefully as the price page.

FDA warning letterFebruary 2026Read it ↗Visit Good Girl Rx
vs

Sesame Care

Higher score

Ranked #5 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care

The verdict for women

Higher Luna Fit Score: Sesame Care

Sesame Care edges out Good Girl Rx on the Luna Fit Score, 85 to 76 (B vs C). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.

Good Girl Rx is still a genuine option — a women-first brand with the clearest contraception guidance we found anywhere in this ranking — and an FDA warning letter for how it labeled its compounded products, which is the reason it does not rank higher. Weigh the six women's-health factors below against your own priorities; what we found reviewing Good Girl Rx goes through each of them, and if neither of these two is the one, our ranked shortlist of Good Girl Rx alternatives widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Good Girl Rx Sesame Care
PCOS & hormonal suitability8584
Good
Sesame
Clinical oversight & labs6888
Good
Sesame
Price transparency7480
Good
Sesame
Nationwide access9292
Good
Sesame
Ongoing support7882
Good
Sesame
Cancellation fairness5585
Good
Sesame

Price, access & features

DetailGood Girl RxSesame Care
Luna Fit Score76/100 · C85/100 · B
Overall rank#60#5
Semaglutide$179/mo month-to-month (from $134/mo on a 12-month prepay)Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)
Tirzepatide$329/mo month-to-month (from $235/mo on a 12-month prepay)Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days
CoverageAll 50 statesNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes

Good Girl Rx

Ranked #60 · Grade C

What we like

  • The best contraception guidance in the ranking: a two-month semaglutide washout before a planned pregnancy, and a warning that tirzepatide can blunt oral contraceptives for four weeks after starting AND after every dose increase
  • Four routes for each molecule — injection, microdose, sublingual dissolving tablet and brand — so a switch does not mean changing provider
  • Publishes a full per-plan price table for every product rather than one headline figure

The caveats

  • Every advertised 'from' price is a 12-month plan paid upfront, and dispensed prescriptions are final sale — a year's commitment with no way back
  • The microdose one-month rate is HIGHER than the standard injection one-month rate; the microdose discount exists only on prepay
  • Prices are described as an 'average monthly cost', so the flat-looking tiers may not be flat

Sesame Care

Ranked #5 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Good Girl Rx nor Sesame Care is only worth comparing with the other. Good Girl Rx is also written up against CoreAge Rx, 17 points apart on the Luna Fit Score — see how Good Girl Rx and CoreAge Rx compare on the Luna Fit Score. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.

Or browse the full comparison hub.