Head-to-head for women
Enhance MD vs ShedRx
Enhance MD and ShedRx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Enhance MD
Higher scoreRanked #2 for women · Grade A−
Luna Fit
Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Visit Enhance MDShedRx
Ranked #9 for women · Grade B
Luna Fit
Best for: Women who want an oral or sublingual option rather than weekly injections, at competitive tirzepatide pricing.
Visit ShedRxThe verdict for women
Enhance MD edges out ShedRx on the Luna Fit Score, 92 to 83 (A− vs B). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.
ShedRx is still a genuine option — a weight-focused program that also offers an oral/sublingual route — a genuine relief for the needle-averse and for anyone easing in gradually. Weigh the six women's-health factors below against your own priorities; the ShedRx scorecard goes through each of them, and if neither of these two is the one, what women pick instead of ShedRx widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Enhance MD | ShedRx |
|---|---|---|
| Luna Fit Score | 92/100 · A− | 83/100 · B |
| Overall rank | #2 | #9 |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $199/mo |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $299/mo |
| Coverage | All 50 states | Not disclosed |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Luna Fit
Enhance MD
Ranked #2 · Grade A−
What we like
- Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
- Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
- Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- No brand-name path and no oral or sublingual route for the needle-averse
- Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start
Luna Fit
ShedRx
Ranked #9 · Grade B
What we like
- Offers oral/sublingual forms — a real alternative to weekly shots
- Competitive tirzepatide pricing
- Weight-focused program with titration support
The caveats
- States-served not disclosed
- Compounded only
- Hormonal/PCOS framing is general, not specialized
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Enhance MD nor ShedRx is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. ShedRx is also written up against CoreAge Rx, 10 points apart — see the ShedRx–CoreAge Rx head-to-head.
- Enhance MD vs CoreAge Rx
- Enhance MD vs yourEra
- Enhance MD vs Sesame Care
- ShedRx vs HealthRX
- ShedRx vs MadeMed
- ShedRx vs Trimi
Or browse the full comparison hub.