Head-to-head for women
Enhance MD vs Trimi
Enhance MD and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Enhance MD
Higher scoreRanked #2 for women · Grade A−
Luna Fit
Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Visit Enhance MDTrimi
Ranked #7 for women · Grade B
Luna Fit
Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.
Visit TrimiThe verdict for women
Enhance MD edges out Trimi on the Luna Fit Score, 92 to 84 (A− vs B). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.
Trimi is still a genuine option — among the lowest verified prices we log — compounded semaglutide and tirzepatide on a single membership, shipped nationwide. A budget-first on-ramp for women who want tirzepatide access without paying a premium. Weigh the six women's-health factors below against your own priorities; what we found reviewing Trimi goes through each of them, and if neither of these two is the one, what women pick instead of Trimi widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Enhance MD | Trimi |
|---|---|---|
| Luna Fit Score | 92/100 · A− | 84/100 · B |
| Overall rank | #2 | #7 |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge) |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Luna Fit
Enhance MD
Ranked #2 · Grade A−
What we like
- Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
- Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
- Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- No brand-name path and no oral or sublingual route for the needle-averse
- Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start
Luna Fit
Trimi
Ranked #7 · Grade B
What we like
- Among the lowest published prices we track on both semaglutide and tirzepatide
- Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
- Nationwide across all 50 states with free shipping
The caveats
- Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
- Injectable only — no oral or sublingual route for the needle-averse
- Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Enhance MD nor Trimi is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.
- Enhance MD vs CoreAge Rx
- Enhance MD vs yourEra
- Enhance MD vs Sesame Care
- Trimi vs HealthRX
- Trimi vs MadeMed
- Trimi vs Found
Or browse the full comparison hub.