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Head-to-head for women

Enhance MD vs Tyde Wellness

Enhance MD and Tyde Wellness both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Enhance MD

Higher score

Ranked #2 for women · Grade A−

Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

Visit Enhance MD
vs

Tyde Wellness

Ranked #23 for women · Grade B

Best for: Women who want an oral or sublingual alternative to weekly shots from a LegitScript-accredited, nationwide provider.

Visit Tyde Wellness

The verdict for women

Higher Luna Fit Score: Enhance MD

Enhance MD edges out Tyde Wellness on the Luna Fit Score, 92 to 86 (A− vs B). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.

Tyde Wellness is still a genuine option — an accredited, all-50-states program that offers an oral option alongside injections — real flexibility for a woman easing into GLP-1 care. Weigh the six women's-health factors below against your own priorities; our Tyde Wellness write-up for women goes through each of them, and if neither of these two is the one, the Tyde Wellness alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Enhance MD Tyde Wellness
PCOS & hormonal suitability9285
Enhance
Tyde
Clinical oversight & labs9487
Enhance
Tyde
Price transparency9484
Enhance
Tyde
Nationwide access9595
Enhance
Tyde
Ongoing support8884
Enhance
Tyde
Cancellation fairness8583
Enhance
Tyde

Price, access & features

DetailEnhance MDTyde Wellness
Luna Fit Score92/100 · A−86/100 · B
Overall rank#2#23
Semaglutide$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay$149/mo
Tirzepatide$329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay$249/mo
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes

Enhance MD

Ranked #2 · Grade A−

What we like

  • Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
  • Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
  • Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • No brand-name path and no oral or sublingual route for the needle-averse
  • Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start

Tyde Wellness

Ranked #23 · Grade B

What we like

  • Offers an oral/sublingual route as well as injections — a genuine option for the needle-averse
  • LegitScript-accredited and available in all 50 states
  • Both molecules disclosed, with tirzepatide for insulin-resistant PCOS

The caveats

  • Mid-to-higher tirzepatide pricing at $249
  • No FDA-approved brand access; general program rather than hormone-specialized

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Enhance MD nor Tyde Wellness is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. Tyde Wellness is also written up against Vaylen, 1 point apart — see the Tyde Wellness–Vaylen head-to-head.

Or browse the full comparison hub.