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Head-to-head for women

MadeMed vs Rx.com

MadeMed and Rx.com both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

MadeMed

Higher score

Ranked #7 for women · Grade B

Best for: Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider.

Visit MadeMed
vs

Rx.com

Ranked #55 for women · Grade C

Best for: A woman who does not want a subscription that re-bills itself, and who values knowing which pharmacy dispenses over paying the lowest sticker.

Visit Rx.com

The verdict for women

Higher Luna Fit Score: MadeMed

MadeMed edges out Rx.com on the Luna Fit Score, 84 to 77 (B vs C). Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider. The reasoning behind that number is in what we found reviewing MadeMed.

Rx.com is still a genuine option — the fairest cancellation terms of anything reviewed here — "No automatic renewals" is printed on the plan card — from a company that also names the pharmacy filling the vial. Weigh the six women's-health factors below against your own priorities; the Rx.com scorecard goes through each of them, and if neither of these two is the one, our ranked shortlist of Rx.com alternatives widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

MadeMed Rx.com
PCOS & hormonal suitability8272
MadeMed
Rx.com
Clinical oversight & labs8074
MadeMed
Rx.com
Price transparency9574
MadeMed
Rx.com
Nationwide access8482
MadeMed
Rx.com
Ongoing support8072
MadeMed
Rx.com
Cancellation fairness8496
MadeMed
Rx.com

Price, access & features

DetailMadeMedRx.com
Luna Fit Score84/100 · B77/100 · C
Overall rank#7#55
Semaglutide$239/mo quarterly (from $199/mo on 6 months)$175/mo month-to-month ($146 only on a six-month prepay)
Tirzepatide$399/mo quarterly (from $369/mo on 6 months)$285/mo month-to-month ($259 only on a six-month prepay)
Coverage40 states49 states on its plan page; its own banner says all 50
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only

MadeMed

Ranked #7 · Grade B

What we like

  • One price at every dose, published dose by dose — semaglutide $239/mo from 0.25mg to 2.4mg, tirzepatide $399/mo from 2.5mg to 15mg
  • LegitScript verified, with board-certified physician review and US compounding pharmacies
  • Oral semaglutide and oral tirzepatide are both offered alongside the injections

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • 40 states rather than nationwide — check yours before you start
  • Tirzepatide is among the pricier entries in this ranking at $399/mo quarterly

Rx.com

Ranked #55 · Grade C

What we like

  • "No automatic renewals" is printed under the plan card itself rather than buried in the terms
  • Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
  • One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included

The caveats

  • The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285
  • The plan page says 49 states served while the banner on the same site says all 50
  • No lab or monitoring protocol is published, and nothing addresses PCOS or the perimenopause transition

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither MadeMed nor Rx.com is only worth comparing with the other. MadeMed is also written up against CoreAge Rx, 9 points apart on the Luna Fit Score — see MadeMed vs CoreAge Rx for women. Rx.com is also written up against CoreAge Rx, 16 points apart — see the Rx.com–CoreAge Rx head-to-head.

Or browse the full comparison hub.