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Head-to-head for women

Rx.com vs yourEra

Rx.com and yourEra both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Rx.com

Ranked #55 for women · Grade C

Best for: A woman who does not want a subscription that re-bills itself, and who values knowing which pharmacy dispenses over paying the lowest sticker.

Visit Rx.com
vs

yourEra

Higher score

Ranked #4 for women · Grade B

Best for: Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account.

Visit yourEra

The verdict for women

Higher Luna Fit Score: yourEra

yourEra edges out Rx.com on the Luna Fit Score, 86 to 77 (B vs C). Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account. The reasoning behind that number is in our full yourEra review.

Rx.com is still a genuine option — the fairest cancellation terms of anything reviewed here — "No automatic renewals" is printed on the plan card — from a company that also names the pharmacy filling the vial. Weigh the six women's-health factors below against your own priorities; the Rx.com scorecard goes through each of them, and if neither of these two is the one, our ranked shortlist of Rx.com alternatives widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Rx.com yourEra
PCOS & hormonal suitability7284
Rx.com
yourEra
Clinical oversight & labs7485
Rx.com
yourEra
Price transparency7488
Rx.com
yourEra
Nationwide access8290
Rx.com
yourEra
Ongoing support7286
Rx.com
yourEra
Cancellation fairness9682
Rx.com
yourEra

Price, access & features

DetailRx.comyourEra
Luna Fit Score77/100 · C86/100 · B
Overall rank#55#4
Semaglutide$175/mo month-to-month ($146 only on a six-month prepay)$199/mo
Tirzepatide$285/mo month-to-month ($259 only on a six-month prepay)$299/mo
Coverage49 states on its plan page; its own banner says all 50All 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only

Rx.com

Ranked #55 · Grade C

What we like

  • "No automatic renewals" is printed under the plan card itself rather than buried in the terms
  • Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
  • One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included

The caveats

  • The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285
  • The plan page says 49 states served while the banner on the same site says all 50
  • No lab or monitoring protocol is published, and nothing addresses PCOS or the perimenopause transition

yourEra

Ranked #4 · Grade B

What we like

  • Publicly listed pricing on both molecules — semaglutide from $199/mo and tirzepatide from $299/mo — while many compounders hide price behind a quiz
  • Fuller menu beyond GLP-1: NAD+ and microdosing protocols, plus an optional membership adding 1:1 coaching, a nutritionist, and an at-home lab draw
  • Markets a 50-state licensed-clinician network, no insurance required, with HSA/FSA accepted

The caveats

  • Compounded semaglutide and tirzepatide are not FDA-approved the way brand Wegovy, Ozempic, or Zepbound are, and compounding access can tighten as brand shortages resolve
  • Mid-market pricing that sits above the cheapest compounders (roughly $99–$150)
  • Injectable only — no oral route and no brand-name lane

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Rx.com nor yourEra is only worth comparing with the other. Rx.com is also written up against CoreAge Rx, 16 points apart on the Luna Fit Score — see the Rx.com–CoreAge Rx head-to-head. yourEra is also written up against CoreAge Rx, 7 points apart — see how yourEra and CoreAge Rx compare on the Luna Fit Score.

Or browse the full comparison hub.