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Head-to-head for women

MadeMed vs RxSpan MD

MadeMed and RxSpan MD both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

MadeMed

Higher score

Ranked #6 for women · Grade B

Best for: Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider.

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vs

RxSpan MD

Ranked #19 for women · Grade B−

Best for: Women who want to be able to check the pharmacy and the prescriber before they buy, and who may want to move between compounded, oral and brand-name options on one account — provided they pick the Monthly plan themselves rather than accepting the prepay the funnel has already selected.

Visit RxSpan MD

The verdict for women

Higher Luna Fit Score: MadeMed

MadeMed edges out RxSpan MD on the Luna Fit Score, 84 to 81 (B vs B−). Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider. The reasoning behind that number is in what we found reviewing MadeMed.

RxSpan MD is still a genuine option — one of the very few programs here that will tell you who compounds your medication and who signs the prescription — four pharmacies named with phone numbers, two physicians named with NPIs that resolve — wrapped around a full menu that runs from compounded semaglutide to brand Zepbound. Weigh the six women's-health factors below against your own priorities; our RxSpan MD write-up for women goes through each of them, and if neither of these two is the one, the full field we rank against RxSpan MD widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

MadeMed RxSpan MD
PCOS & hormonal suitability8278
MadeMed
RxSpan
Clinical oversight & labs8084
MadeMed
RxSpan
Price transparency9576
MadeMed
RxSpan
Nationwide access8492
MadeMed
RxSpan
Ongoing support8082
MadeMed
RxSpan
Cancellation fairness8476
MadeMed
RxSpan

Price, access & features

DetailMadeMedRxSpan MD
Luna Fit Score84/100 · B81/100 · B−
Overall rank#6#19
Semaglutide$239/mo quarterly (from $199/mo on 6 months)$249/mo month-to-month (3/6/12-month prepay: $219/$199/$194 per month, billed $657/$1,194/$2,327 up front)
Tirzepatide$399/mo quarterly (from $369/mo on 6 months)$329/mo month-to-month (3/6/12-month prepay: $309/$289/$269 per month, billed $927/$1,734/$3,228 up front)
Coverage40 statesAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes

MadeMed

Ranked #6 · Grade B

What we like

  • One price at every dose, published dose by dose — semaglutide $239/mo from 0.25mg to 2.4mg, tirzepatide $399/mo from 2.5mg to 15mg
  • LegitScript verified, with board-certified physician review and US compounding pharmacies
  • Oral semaglutide and oral tirzepatide are both offered alongside the injections

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • 40 states rather than nationwide — check yours before you start
  • Tirzepatide is among the pricier entries in this ranking at $399/mo quarterly

RxSpan MD

Ranked #19 · Grade B−

What we like

  • Four dispensing pharmacies named outright, with phone numbers — Belmar, Strive, Epiq Scripts and Casa Pharma Rx — where most of this ranking says only "our partner pharmacies"
  • The prescribing group is named too, and checkable: Lion MD, led by Dr Ana Lisa Carr, MD (NPI 1689841744) with Dr Kelly Tenbrink, MD (NPI 1346482684). Both resolve as active physicians in the federal NPPES registry
  • A real brand-name lane with prices on the page rather than an enquiry form — Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069 a month — alongside the compounded line, so switching does not mean switching provider

The caveats

  • The plan selector arrives with the 3-month prepay already chosen, not Monthly, and badges the 3-, 6- and 12-month tiers alike as "Max Saving" — so the default path takes $657 up front rather than $249, and the headline figures are footnoted "(For the first month)"
  • Its FAQ says "no long-term commitments" on the same site where the 12-month semaglutide plan is a single $2,327 charge and the 12-month tirzepatide plan is $3,228. The freedom is real on the monthly plan; it is not what the prepay tiers are
  • Brand-name bundles carry a $50 medical review fee if a clinician does not end up prescribing for you — worth knowing before you start an intake for Wegovy or Zepbound

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither MadeMed nor RxSpan MD is only worth comparing with the other. MadeMed is also written up against CoreAge Rx, 9 points apart on the Luna Fit Score — see MadeMed vs CoreAge Rx for women. RxSpan MD is also written up against CoreAge Rx, 12 points apart — see the RxSpan MD–CoreAge Rx head-to-head.

Or browse the full comparison hub.