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Head-to-head for women

RxSpan MD vs yourEra

RxSpan MD and yourEra both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

RxSpan MD

Ranked #19 for women · Grade B−

Best for: Women who want to be able to check the pharmacy and the prescriber before they buy, and who may want to move between compounded, oral and brand-name options on one account — provided they pick the Monthly plan themselves rather than accepting the prepay the funnel has already selected.

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vs

yourEra

Higher score

Ranked #3 for women · Grade B

Best for: Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account.

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The verdict for women

Higher Luna Fit Score: yourEra

yourEra edges out RxSpan MD on the Luna Fit Score, 86 to 81 (B vs B−). Women who want transparently priced semaglutide and tirzepatide plus an optional NAD+, microdosing, and coaching-and-labs menu on one account. The reasoning behind that number is in our full yourEra review.

RxSpan MD is still a genuine option — one of the very few programs here that will tell you who compounds your medication and who signs the prescription — four pharmacies named with phone numbers, two physicians named with NPIs that resolve — wrapped around a full menu that runs from compounded semaglutide to brand Zepbound. Weigh the six women's-health factors below against your own priorities; our RxSpan MD write-up for women goes through each of them, and if neither of these two is the one, the full field we rank against RxSpan MD widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

RxSpan MD yourEra
PCOS & hormonal suitability7884
RxSpan
yourEra
Clinical oversight & labs8485
RxSpan
yourEra
Price transparency7688
RxSpan
yourEra
Nationwide access9290
RxSpan
yourEra
Ongoing support8286
RxSpan
yourEra
Cancellation fairness7682
RxSpan
yourEra

Price, access & features

DetailRxSpan MDyourEra
Luna Fit Score81/100 · B−86/100 · B
Overall rank#19#3
Semaglutide$249/mo month-to-month (3/6/12-month prepay: $219/$199/$194 per month, billed $657/$1,194/$2,327 up front)$199/mo
Tirzepatide$329/mo month-to-month (3/6/12-month prepay: $309/$289/$269 per month, billed $927/$1,734/$3,228 up front)$299/mo
CoverageAll 50 statesAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only

RxSpan MD

Ranked #19 · Grade B−

What we like

  • Four dispensing pharmacies named outright, with phone numbers — Belmar, Strive, Epiq Scripts and Casa Pharma Rx — where most of this ranking says only "our partner pharmacies"
  • The prescribing group is named too, and checkable: Lion MD, led by Dr Ana Lisa Carr, MD (NPI 1689841744) with Dr Kelly Tenbrink, MD (NPI 1346482684). Both resolve as active physicians in the federal NPPES registry
  • A real brand-name lane with prices on the page rather than an enquiry form — Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069 a month — alongside the compounded line, so switching does not mean switching provider

The caveats

  • The plan selector arrives with the 3-month prepay already chosen, not Monthly, and badges the 3-, 6- and 12-month tiers alike as "Max Saving" — so the default path takes $657 up front rather than $249, and the headline figures are footnoted "(For the first month)"
  • Its FAQ says "no long-term commitments" on the same site where the 12-month semaglutide plan is a single $2,327 charge and the 12-month tirzepatide plan is $3,228. The freedom is real on the monthly plan; it is not what the prepay tiers are
  • Brand-name bundles carry a $50 medical review fee if a clinician does not end up prescribing for you — worth knowing before you start an intake for Wegovy or Zepbound

yourEra

Ranked #3 · Grade B

What we like

  • Publicly listed pricing on both molecules — semaglutide from $199/mo and tirzepatide from $299/mo — while many compounders hide price behind a quiz
  • Fuller menu beyond GLP-1: NAD+ and microdosing protocols, plus an optional membership adding 1:1 coaching, a nutritionist, and an at-home lab draw
  • Markets a 50-state licensed-clinician network, no insurance required, with HSA/FSA accepted

The caveats

  • Compounded semaglutide and tirzepatide are not FDA-approved the way brand Wegovy, Ozempic, or Zepbound are, and compounding access can tighten as brand shortages resolve
  • Mid-market pricing that sits above the cheapest compounders (roughly $99–$150)
  • Injectable only — no oral route and no brand-name lane

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither RxSpan MD nor yourEra is only worth comparing with the other. RxSpan MD is also written up against CoreAge Rx, 12 points apart on the Luna Fit Score — see the RxSpan MD–CoreAge Rx head-to-head. yourEra is also written up against CoreAge Rx, 7 points apart — see how yourEra and CoreAge Rx compare on the Luna Fit Score.

Or browse the full comparison hub.