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Head-to-head for women
MadeMed vs System Labs
MadeMed and System Labs both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
MadeMed
Higher scoreRanked #7 for women · Grade B
Luna Fit
Best for: Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider.
Visit MadeMedSystem Labs
Ranked #18 for women · Grade B−
Luna Fit
Best for: Women who want one predictable monthly cost that does not climb as they titrate, and who are comfortable with a single compounded GLP-1/GIP injection rather than a choice of named molecules.
Visit System LabsThe verdict for women
MadeMed edges out System Labs on the Luna Fit Score, 84 to 81 (B vs B−). Women who expect to titrate and want to know today what month six costs, and who want an oral route available without switching provider. The reasoning behind that number is in what we found reviewing MadeMed.
System Labs is still a genuine option — a flat $179 a month at every dose, with the ongoing rate stated in writing rather than buried under an intro price — and you can cancel from your own dashboard, which is more than most of this ranking will commit to. Weigh the six women's-health factors below against your own priorities; our System Labs write-up for women goes through each of them, and if neither of these two is the one, the alternatives to System Labs we rank for women widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | MadeMed | System Labs |
|---|---|---|
| Luna Fit Score | 84/100 · B | 81/100 · B− |
| Overall rank | #7 | #18 |
| Semaglutide | $239/mo quarterly (from $199/mo on 6 months) | Not offered — the one GLP-1 product is a compounded GLP-1/GIP and no semaglutide is sold |
| Tirzepatide | $399/mo quarterly (from $369/mo on 6 months) | GLP-1/GIP $179/mo flat ($99 first month) |
| Coverage | 40 states | Not publicly listed |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Luna Fit
MadeMed
Ranked #7 · Grade B
What we like
- One price at every dose, published dose by dose — semaglutide $239/mo from 0.25mg to 2.4mg, tirzepatide $399/mo from 2.5mg to 15mg
- LegitScript verified, with board-certified physician review and US compounding pharmacies
- Oral semaglutide and oral tirzepatide are both offered alongside the injections
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- 40 states rather than nationwide — check yours before you start
- Tirzepatide is among the pricier entries in this ranking at $399/mo quarterly
Luna Fit
System Labs
Ranked #18 · Grade B−
What we like
- One flat price at every dose — the plan is sold as a "Monthly Supply (All doses)", so titrating up does not quietly raise the bill
- The ongoing rate is stated, not implied: their own FAQ says the subscription is billed at a flat $179/mo with no hidden fees
- Pause or cancel yourself from the dashboard at any time — no phone call, no retention queue
The caveats
- Compounded medication is not FDA-approved, and the site says so plainly in its own FDA disclosure
- The molecule is never named — it is sold only as "compounded GLP-1/GIP", so you cannot compare it against a semaglutide or tirzepatide price anywhere else in this ranking
- The headline price is a first-month teaser: $99 for month one against a $179 standing rate, so budget for $179 rather than the number in the hero
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither MadeMed nor System Labs is only worth comparing with the other. MadeMed is also written up against CoreAge Rx, 9 points apart on the Luna Fit Score — see MadeMed vs CoreAge Rx for women. System Labs is also written up against CoreAge Rx, 12 points apart — see the System Labs–CoreAge Rx head-to-head.
- MadeMed vs CoreAge Rx
- MadeMed vs Enhance MD
- MadeMed vs Eden
- System Labs vs yourEra
- System Labs vs Sesame Care
- System Labs vs HealthRX
Or browse the full comparison hub.