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System Labs review
By Luna Editorial Team, PublisherUpdated Partner
A flat $179 a month at every dose after the $99 first month, with medication, supplies and shipping included; its FAQ now names a pharmacy and qualified nationwide access, but cancellation instructions disagree across its pages.
What System Labs costs
- Semaglutide
- Not offered — the one GLP-1 product is a compounded GLP-1/GIP and no semaglutide is sold
- Tirzepatide
- GLP-1/GIP $179/mo flat ($99 first month)
- Where it treats
- All 50 US states per FAQ; specific treatments depend on state rules and pharmacy licensing
- Brand-name GLP-1s
- Compounded only
How System Labs scores for women
Six women's-health factors, weighted as in our methodology.
What we like
- Flat $179/mo standing rate at every dose, after the $99 first month
- Medication, supplies, clinician support and free two-day temperature-controlled shipping included
- General FAQ names The Pharmacy Hub as a pharmacy partner
- FAQ states qualified coverage in all 50 states and says clinicians can order labs when required
The caveats
- Product is labeled compounded GLP-1/GIP without naming the molecule; confirm the exact prescription
- Compounded medication is not FDA-approved; no confirmed brand-name or oral GLP-1 option on the product page
- Landing page promises dashboard cancellation, while the FAQ directs email and says self-service is coming soon
- Services already provided and prescriptions already ordered are non-refundable under its FAQ
- No defined PCOS or menopause program, and routine lab monitoring is not included as a clear base-plan benefit
The full review
System Labs sells a single compounded weight-management injection under the description GLP-1/GIP. It is built around a simple subscription: a lower first-month charge, one standing price at every dose and medication delivered with supplies. Its public pages are less consistent about how you cancel. The weight-loss page promises dashboard cancellation, while the general FAQ says to email support and describes self-service cancellation as a future feature.
How much does System Labs cost?
The advertised offer is $99 for the first month, then $179 a month. The weight-loss FAQ explicitly identifies $179 as the flat recurring rate, so that is the figure to use for ongoing budgeting. Treat the opening $99 as an introductory discount rather than the normal monthly cost.
The listed subscription includes a monthly supply at all doses, injection supplies, clinician support and free two-day temperature-controlled shipping. The company says there are no hidden fees. It does not publish a different price for each dose on that page, which makes the core subscription easier to compare than a low-dose teaser with later increases.
A discount toward a Rythm blood test appears in the program's wider offering, but a discount is not an included baseline lab panel. Ask which tests your clinician needs, where they are performed and whether you pay the lab separately. The general FAQ says some therapies require tests and that a provider can order them.
If you are comparing a first-month offer elsewhere, look beyond the first refill. Three months at the published System Labs offer would total $457 before any separately billed tests: $99 followed by two $179 charges. That is arithmetic from the posted terms, not a promise about an individualized treatment plan.
What medication is actually offered?
The product page calls the treatment compounded GLP-1/GIP and does not give a specific molecule name. It should not be quoted as a semaglutide product or compared as a confirmed tirzepatide formulation without asking the prescriber what you will receive.
Brand-name drugs appear in explanatory comparisons, but that does not mean the displayed $179 plan supplies Wegovy or Zepbound. The actual offer is compounded. The footer states that these therapies are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness or quality.
Ask for the active ingredient, concentration, any added ingredients and the pharmacy dispensing your order before you agree to a prescription. Those details matter more than the marketing phrase GLP-1/GIP. A weekly injection schedule does not establish that two vials from different programs contain interchangeable concentrations.
Who provides the care?
System Labs describes licensed physicians, nurse practitioners and physician assistants who review medical history and assess whether treatment is appropriate. The landing page presents a medical team, and the FAQ says provider education, residency and licensing information is available on request and in the patient portal.
The stated flow is to choose a treatment, complete a detailed intake and then be offered a telemedicine consultation with someone licensed in your state. A prescription is not guaranteed. The clinician may refer you to in-person care if necessary, and patients can contact the care team with safety concerns.
The company describes follow-ups and monitoring as part of the model, but does not publish a fixed number of scheduled live appointments for the $179 plan. Before enrolling, ask what ongoing support means in practice: a recurring visit, messages when needed or a refill questionnaire. This assessment covers the published care model.
Want to see System Labs's plans and intake for yourself?
Visit System LabsWhich pharmacy fills the medication?
The general FAQ names The Pharmacy Hub as its compounding pharmacy partner. It also says clinicians may send prescriptions to retail pharmacies when appropriate and patients can discuss an alternative pharmacy. That is a better disclosure than an unnamed nationwide network, though it does not independently establish licensing or testing for your particular prescription.
The company says its pharmacies use third-party testing. Ask what information is available for the batch you receive and who answers questions about storage or injection instructions. The prescribing clinician and the dispensing pharmacist have different roles, and you should be able to reach both.
Is System Labs a fit for PCOS or menopause?
Its main public menu centers on weight management and longevity-oriented treatments such as NAD+, sermorelin and glutathione. We did not find a defined PCOS workup, a menopause hormone-replacement program or an ongoing gynecology service in the reviewed material.
That makes it easier to consider as a separate medication service if you already have a clinician handling hormonal symptoms. It is a weaker starting point if your real question is why periods are irregular, whether thyroid disease contributes to weight gain or whether menopause treatment is appropriate.
Do not read the site's discussion of gut hormones as evidence of comprehensive women's hormonal care. Our women's provider guide separates those services, and the menopause comparison helps if midlife symptom care is part of your goal. Ask who reviews your existing prescriptions and who coordinates changes with your usual clinician.
Where is it available?
The general FAQ says System Labs is available across all 50 US states, with individual treatments depending on telehealth regulations and pharmacy licensing. The intake confirms eligibility for the specific prescription. That qualification matters: a clinician's nationwide licensure does not itself guarantee every medication can ship everywhere.
The program is promoted without insurance requirements. Confirm HSA or FSA eligibility with your administrator if that is how you intend to pay. A low cash price is not an insurance benefit, and the public plan description does not promise reimbursement paperwork or prior-authorization support.
How do cancellation and refunds work?
The weight-loss landing page says you can pause or cancel from the dashboard at any time. The broader FAQ instead directs you to contact support and says a Stripe self-cancellation portal will be available soon. Until your account actually shows that control, keep an email-based cancellation route and request written confirmation.
The refund FAQ says completed services and prescriptions already ordered are non-refundable. If you have paid for a service not yet received, support will review the request rather than promise an automatic refund in every case. Prescription medications cannot be returned once dispensed.
Before your first refill, establish the next charge date and the stage at which a pharmacy order becomes final. The public pages do not give a clear universal advance-notice window. A simple monthly price is useful, but the cancellation path and refund cutoff also belong in the decision.
Where it lands
System Labs offers an understandable standing subscription price and now publishes both a pharmacy partner and qualified nationwide availability. The unresolved points are the exact formulation, what monitoring includes and which cancellation instruction governs your account. It is a reasonable comparison for a woman seeking a separate compounded medication service, with stronger specialist alternatives if diagnosis and menopause or PCOS care need to happen together.
Our verdict on System Labs
Best for: Women who want one predictable monthly cost that does not climb as they titrate, and who are comfortable with a single compounded GLP-1/GIP injection rather than a choice of named molecules.
Listed #13 of 88 providers we reviewed for women — compare with CoreAge Rx. Cancellation fairness is where System Labs scores lowest, at 75/100. If that is your sticking point, start with what women pick instead of System Labs.
Related guides
- Semaglutide vs Tirzepatide for Women: Insulin Resistance and ResultsHow semaglutide and tirzepatide compare for women — mechanism, weight-loss results and why insulin resistance shapes the choice.Read the guide
- How to Choose a GLP-1 Provider as a WomanA women's-health checklist for picking a GLP-1 provider: hormonal suitability, labs, clinical oversight and price — not just the cheapest vial.Read the guide
- Compounded Semaglutide Cost in 2026: What Programs Actually Charge Each MonthCompounded semaglutide costs $129 to $297 a month across 22 telehealth programs we review, median $177. Price bands, billing traps and the FDA rules.Read the guide
- Ozempic, Wegovy and Zepbound Side Effects in Women: What's Different and What's NormalNausea, hair shedding, period changes, gallstones, bone and muscle, mood, libido and "Ozempic face": what women report on GLP-1s and when to call.Read the guide
Others in System Labs's score range
The providers scoring closest to System Labs on the same six factors. One of those comparisons is written out in full: the System Labs–CoreAge Rx head-to-head, 11 points apart on the Luna Fit Score. Directly below System Labs sits Ondra Health at #14 with 88/100 — see the full field we rank against Ondra Health if that is the band you are shopping in.
Shed83/100
Strut Health83/100
yourEra82/100
Alloy82/100
Elara Health and Wellness82/100
Renlo Health82/100
See all 88 providers we've reviewed for women — scored on the same rubric, with prices side by side.
Prices and states reflect System Labs's own public pages when we last checked them; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on System Labs's site. Not medical advice; see our disclosure.