Skip to content
Luna Metabolic
Menu

Head-to-head for women

PepHaūs vs Sesame Care

PepHaūs and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

PepHaūs

Ranked #30 for women · Grade B

Best for: Women who want a LegitScript-accredited, all-50-states provider with clear pricing on both molecules.

Visit PepHaūs
vs

Sesame Care

Ranked #4 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care

The verdict for women

PepHaūs and Sesame Care tie on the Luna Fit Score at 85/100 apiece, so neither runs away with it. The right pick comes down to the factors that matter most to you — compare them below, or read the PepHaūs scorecard and the Sesame Care scorecard in full. If the answer is still neither, the PepHaūs alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

PepHaūs Sesame Care
PCOS & hormonal suitability8384
PepHaūs
Sesame
Clinical oversight & labs8588
PepHaūs
Sesame
Price transparency8480
PepHaūs
Sesame
Nationwide access9592
PepHaūs
Sesame
Ongoing support8382
PepHaūs
Sesame
Cancellation fairness8285
PepHaūs
Sesame

Price, access & features

DetailPepHaūsSesame Care
Luna Fit Score85/100 · B85/100 · B
Overall rank#30#4
Semaglutide$152/moCare $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg
Tirzepatide$246/moCare $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg)
CoverageAll 50 statesNationwide marketplace
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes

PepHaūs

Ranked #30 · Grade B

What we like

  • LegitScript-accredited and available nationwide
  • Both semaglutide and tirzepatide disclosed at fair mid-market pricing
  • Tirzepatide included for insulin-resistant PCOS

The caveats

  • No oral route or brand-name access
  • General metabolic focus, not hormone-specialized

Sesame Care

Ranked #4 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither PepHaūs nor Sesame Care is only worth comparing with the other. PepHaūs is also written up against CoreAge Rx, 8 points apart on the Luna Fit Score — see PepHaūs against CoreAge Rx, factor by factor. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.

Or browse the full comparison hub.