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Head-to-head for women

Ro vs Sesame Care

Ro and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Ro

Higher score

Ranked #28 for women · Grade B

Best for: Women who want brand-name medication and insurance support, and are comfortable with a big, polished platform.

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vs

Sesame Care

Ranked #4 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

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The verdict for women

Higher Luna Fit Score: Ro

Ro edges out Sesame Care on the Luna Fit Score, 86 to 85 (B vs B). Women who want brand-name medication and insurance support, and are comfortable with a big, polished platform. The reasoning behind that number is in our full Ro review.

Sesame Care is still a genuine option — an established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency. Weigh the six women's-health factors below against your own priorities; the Sesame Care scorecard goes through each of them, and if neither of these two is the one, the Sesame Care alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Ro Sesame Care
PCOS & hormonal suitability8884
Ro
Sesame
Clinical oversight & labs8888
Ro
Sesame
Price transparency7880
Ro
Sesame
Nationwide access8892
Ro
Sesame
Ongoing support8782
Ro
Sesame
Cancellation fairness8585
Ro
Sesame

Price, access & features

DetailRoSesame Care
Luna Fit Score86/100 · B85/100 · B
Overall rank#28#4
SemaglutideNot disclosedCare $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) — plus the drug: brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg
TirzepatideNot disclosedCare $59/mo on the 12-month prepay, otherwise $99 per 28 days — plus the drug: brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg)
CoverageMulti-stateNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes

Ro

Ranked #28 · Grade B

What we like

  • Brand-name (Wegovy/Zepbound) access and insurance navigation
  • Oral options and a well-funded, polished experience
  • Strong clinical infrastructure

The caveats

  • Does not publicly disclose compounded pricing up front
  • Premium positioning

Sesame Care

Ranked #4 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Ro nor Sesame Care is only worth comparing with the other. Ro is also written up against Eden, 2 points apart on the Luna Fit Score — see the Ro–Eden head-to-head. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.

Or browse the full comparison hub.