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Head-to-head for women

Synergy Rx vs Enhance MD

Synergy Rx and Enhance MD both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Synergy Rx

Ranked #38 for women · Grade C

Best for: Women who specifically want a brand-name path and unlimited clinical contact, and who are prepared to get pricing by enquiry.

Visit Synergy Rx
vs

Enhance MD

Higher score

Ranked #2 for women · Grade A−

Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

Visit Enhance MD

The verdict for women

Higher Luna Fit Score: Enhance MD

Enhance MD edges out Synergy Rx on the Luna Fit Score, 92 to 76 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

Synergy Rx is still a genuine option — one of the few programmes here that will prescribe brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited 24/7 access to its clinical team — though you will not find a GLP-1 price anywhere on its site. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Synergy Rx Enhance MD
PCOS & hormonal suitability8092
Synergy
Enhance
Clinical oversight & labs8294
Synergy
Enhance
Price transparency5894
Synergy
Enhance
Nationwide access7495
Synergy
Enhance
Ongoing support9088
Synergy
Enhance
Cancellation fairness7085
Synergy
Enhance

Price, access & features

DetailSynergy RxEnhance MD
Luna Fit Score76/100 · C92/100 · A−
Overall rank#38#2
SemaglutideFrom $199/mo$212/mo
TirzepatideFrom $349/mo$280/mo
CoverageNot disclosedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only

Synergy Rx

Ranked #38 · Grade C

What we like

  • Will prescribe FDA-approved brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate — rare on this board
  • Unlimited appointments, messaging and 24/7 access to a dedicated clinical team
  • FSA and HSA eligible

The caveats

  • Publishes no GLP-1 price on its own site — the longevity line is priced openly, the medication this page is about is not
  • At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves

Enhance MD

Ranked #2 · Grade A−

What we like

  • Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
  • Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
  • Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • No brand-name path and no oral or sublingual route for the needle-averse
  • Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score; affiliate partners carry a capped 6-point edge in list order, never in the score itself. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing Synergy Rx and Enhance MD against other providers we review for women.

Or browse the full comparison hub.