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Head-to-head for women
Synergy Rx vs Trimi
Synergy Rx and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Synergy Rx
Ranked #44 for women · Grade C
Luna Fit
Best for: Women who specifically want a brand-name path and unlimited clinical contact, and who are prepared to get pricing by enquiry.
Visit Synergy RxTrimi
Higher scoreRanked #8 for women · Grade B
Luna Fit
Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.
Visit TrimiThe verdict for women
Trimi edges out Synergy Rx on the Luna Fit Score, 84 to 76 (B vs C). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes. The reasoning behind that number is in what we found reviewing Trimi.
Synergy Rx is still a genuine option — one of the few programs here that will prescribe brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited 24/7 access to its clinical team — though you will not find a GLP-1 price anywhere on its site. Weigh the six women's-health factors below against your own priorities; our Synergy Rx write-up for women goes through each of them, and if neither of these two is the one, the Synergy Rx alternatives, scored on the same six factors widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Synergy Rx | Trimi |
|---|---|---|
| Luna Fit Score | 76/100 · C | 84/100 · B |
| Overall rank | #44 | #8 |
| Semaglutide | From $199/mo | $175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge) |
| Tirzepatide | From $349/mo | $235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge) |
| Coverage | Not disclosed | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Luna Fit
Synergy Rx
Ranked #44 · Grade C
What we like
- Will prescribe FDA-approved brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate — rare in this ranking
- Unlimited appointments, messaging and 24/7 access to a dedicated clinical team
- FSA and HSA eligible
The caveats
- Publishes no GLP-1 price on its own site — the longevity line is priced openly, the medication this page is about is not
- At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
Luna Fit
Trimi
Ranked #8 · Grade B
What we like
- Among the lowest published prices we track on both semaglutide and tirzepatide
- Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
- Nationwide across all 50 states with free shipping
The caveats
- Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
- Injectable only — no oral or sublingual route for the needle-averse
- Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Synergy Rx nor Trimi is only worth comparing with the other. Synergy Rx is also written up against CoreAge Rx, 17 points apart on the Luna Fit Score — see Synergy Rx against CoreAge Rx, factor by factor. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.
- Synergy Rx vs CoreAge Rx
- Synergy Rx vs Enhance MD
- Synergy Rx vs Eden
- Trimi vs yourEra
- Trimi vs Sesame Care
- Trimi vs HealthRX
Or browse the full comparison hub.