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Head-to-head for women

Synergy Rx vs Trimi

Synergy Rx and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Synergy Rx

Ranked #38 for women · Grade C

Best for: Women who specifically want a brand-name path and unlimited clinical contact, and who are prepared to get pricing by enquiry.

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vs

Trimi

Higher score

Ranked #9 for women · Grade B

Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.

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The verdict for women

Higher Luna Fit Score: Trimi

Trimi edges out Synergy Rx on the Luna Fit Score, 84 to 76 (B vs C). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.

Synergy Rx is still a genuine option — one of the few programmes here that will prescribe brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited 24/7 access to its clinical team — though you will not find a GLP-1 price anywhere on its site. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Synergy Rx Trimi
PCOS & hormonal suitability8084
Synergy
Trimi
Clinical oversight & labs8278
Synergy
Trimi
Price transparency5892
Synergy
Trimi
Nationwide access7490
Synergy
Trimi
Ongoing support9080
Synergy
Trimi
Cancellation fairness7080
Synergy
Trimi

Price, access & features

DetailSynergy RxTrimi
Luna Fit Score76/100 · C84/100 · B
Overall rank#38#9
SemaglutideFrom $199/mo$129/mo
TirzepatideFrom $349/mo$229/mo
CoverageNot disclosedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only

Synergy Rx

Ranked #38 · Grade C

What we like

  • Will prescribe FDA-approved brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate — rare on this board
  • Unlimited appointments, messaging and 24/7 access to a dedicated clinical team
  • FSA and HSA eligible

The caveats

  • Publishes no GLP-1 price on its own site — the longevity line is priced openly, the medication this page is about is not
  • At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves

Trimi

Ranked #9 · Grade B

What we like

  • Among the lowest published prices we track on both semaglutide and tirzepatide
  • Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
  • Nationwide across all 50 states with free shipping

The caveats

  • Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
  • Injectable only — no oral or sublingual route for the needle-averse
  • Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Luna Fit Score; affiliate partners carry a capped 6-point edge in list order, never in the score itself. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing Synergy Rx and Trimi against other providers we review for women.

Or browse the full comparison hub.