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Head-to-head for women
Enhance MD vs Synergy Rx
Enhance MD and Synergy Rx both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
Enhance MD
Higher scoreRanked #2 for women · Grade A−
Luna Fit
Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.
Visit Enhance MDSynergy Rx
Ranked #44 for women · Grade C
Luna Fit
Best for: Women who specifically want a brand-name path and unlimited clinical contact, and who are prepared to get pricing by enquiry.
Visit Synergy RxThe verdict for women
Enhance MD edges out Synergy Rx on the Luna Fit Score, 92 to 76 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.
Synergy Rx is still a genuine option — one of the few programs here that will prescribe brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited 24/7 access to its clinical team — though you will not find a GLP-1 price anywhere on its site. Weigh the six women's-health factors below against your own priorities; our Synergy Rx write-up for women goes through each of them, and if neither of these two is the one, the Synergy Rx alternatives, scored on the same six factors widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Enhance MD | Synergy Rx |
|---|---|---|
| Luna Fit Score | 92/100 · A− | 76/100 · C |
| Overall rank | #2 | #44 |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | From $199/mo |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | From $349/mo |
| Coverage | All 50 states | Not disclosed |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Luna Fit
Enhance MD
Ranked #2 · Grade A−
What we like
- Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
- Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
- Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff
The caveats
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- No brand-name path and no oral or sublingual route for the needle-averse
- Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start
Luna Fit
Synergy Rx
Ranked #44 · Grade C
What we like
- Will prescribe FDA-approved brand-name Wegovy, Ozempic or Mounjaro when clinically appropriate — rare in this ranking
- Unlimited appointments, messaging and 24/7 access to a dedicated clinical team
- FSA and HSA eligible
The caveats
- Publishes no GLP-1 price on its own site — the longevity line is priced openly, the medication this page is about is not
- At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
- Does not publish which states it serves
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither Enhance MD nor Synergy Rx is only worth comparing with the other. Enhance MD is also written up against CoreAge Rx, 1 point apart on the Luna Fit Score — see the Enhance MD–CoreAge Rx head-to-head. Synergy Rx is also written up against CoreAge Rx, 17 points apart — see Synergy Rx against CoreAge Rx, factor by factor.
- Enhance MD vs CoreAge Rx
- Enhance MD vs Eden
- Enhance MD vs yourEra
- Synergy Rx vs Sesame Care
- Synergy Rx vs HealthRX
- Synergy Rx vs MadeMed
Or browse the full comparison hub.