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Head-to-head for women

System Labs vs HealthRX

System Labs and HealthRX both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

System Labs

Ranked #18 for women · Grade B−

Best for: Women who want one predictable monthly cost that does not climb as they titrate, and who are comfortable with a single compounded GLP-1/GIP injection rather than a choice of named molecules.

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vs

HealthRX

Higher score

Ranked #5 for women · Grade B

Best for: Women who want a LegitScript-certified, physician-supervised program with both molecules, an oral-tablet route as well as injections, and transparent flat pricing with no insurance to navigate.

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The verdict for women

Higher Luna Fit Score: HealthRX

HealthRX edges out System Labs on the Luna Fit Score, 85 to 81 (B vs B−). Women who want a LegitScript-certified, physician-supervised program with both molecules, an oral-tablet route as well as injections, and transparent flat pricing with no insurance to navigate.

System Labs is still a genuine option — a flat $179 a month at every dose, with the ongoing rate stated in writing rather than buried under an intro price — and you can cancel from your own dashboard, which is more than most of this board will commit to. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

System Labs HealthRX
PCOS & hormonal suitability7886
System
HealthRX
Clinical oversight & labs8287
System
HealthRX
Price transparency8486
System
HealthRX
Nationwide access7480
System
HealthRX
Ongoing support8485
System
HealthRX
Cancellation fairness8884
System
HealthRX

Price, access & features

DetailSystem LabsHealthRX
Luna Fit Score81/100 · B−85/100 · B
Overall rank#18#5
SemaglutideNot disclosed$189/mo
TirzepatideGLP-1/GIP $179/mo flat ($99 first month)$349/mo
CoverageNot publicly listedNot publicly listed
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes

System Labs

Ranked #18 · Grade B−

What we like

  • One flat price at every dose — the plan is sold as a "Monthly Supply (All doses)", so titrating up does not quietly raise the bill
  • The ongoing rate is stated, not implied: their own FAQ says the subscription is billed at a flat $179/mo with no hidden fees
  • Pause or cancel yourself from the dashboard at any time — no phone call, no retention queue

The caveats

  • Compounded medication is not FDA-approved, and the site says so plainly in its own FDA disclosure
  • The molecule is never named — it is sold only as "compounded GLP-1/GIP", so you cannot compare it against a semaglutide or tirzepatide price anywhere else on this board
  • The headline price is a first-month teaser: $99 for month one against a $179 standing rate, so budget for $179 rather than the number in the hero
Visit System Labs Full review →

HealthRX

Ranked #5 · Grade B

What we like

  • LegitScript-certified (a meaningful third-party trust signal) with physician-supervised care, not a prescription-only handoff
  • Both molecules plus a rare oral GLP-1 tablet — real optionality for the needle-averse and for insulin-resistant PCOS
  • Transparent, no-insurance flat pricing — injectable GLP-1 around $189/mo, oral tablet around $239/mo, GLP+GIP around $349/mo

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • Some tiers are company-stated and the public site is thin, so a few figures can't be verified live
  • Brand-name tiers are pass-through and expensive — brand Ozempic runs about $1,299/mo
Visit HealthRX Full review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing System Labs and HealthRX against other providers we review for women.

Or browse the full comparison hub.