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Head-to-head for women

Alloy vs Sesame Care

Alloy and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Alloy

Ranked #41 for women · Grade B−

Best for: Women in perimenopause or menopause who want the clinician managing their weight to be the same one who understands their hormones — and who can absorb a membership fee on top of the drug price.

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vs

Sesame Care

Higher score

Ranked #4 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care

The verdict for women

Higher Luna Fit Score: Sesame Care

Sesame Care edges out Alloy on the Luna Fit Score, 85 to 82 (B vs B−). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.

Alloy is still a genuine option — the only program on this board built for midlife first: your prescriber is a Menopause Society–certified physician, and weight care sits alongside a full hormone-therapy line rather than being sold in isolation. Weigh the six women's-health factors below against your own priorities; what we found reviewing Alloy goes through each of them, and if neither of these two is the one, the Alloy alternatives, scored on the same six factors widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Alloy Sesame Care
PCOS & hormonal suitability8884
Alloy
Sesame
Clinical oversight & labs8488
Alloy
Sesame
Price transparency7880
Alloy
Sesame
Nationwide access7092
Alloy
Sesame
Ongoing support9382
Alloy
Sesame
Cancellation fairness7685
Alloy
Sesame

Price, access & features

DetailAlloySesame Care
Luna Fit Score82/100 · B−85/100 · B
Overall rank#41#4
SemaglutideFrom $169/mo all-in ($70 medication + $99 membership)From $149/mo (brand Wegovy pill)
TirzepatideFrom $199/mo all-in ($100 medication + $99 membership)Brand Zepbound (price varies)
CoverageNot disclosed; compounded excluded in 6 states and DCNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes

Alloy

Ranked #41 · Grade B−

What we like

  • Prescribers hold the Menopause Society Certified Practitioner credential — the only board entry where that is true of named clinicians
  • The widest formulary here: compounded semaglutide, tirzepatide and liraglutide, plus brand Wegovy, Zepbound and the Wegovy and Foundayo pills
  • Oral routes are FDA-approved brand pills, not a compounded workaround, for women who will not inject

The caveats

  • The $99/mo membership is charged on top of every medication price, so the headline figure is not what you pay
  • Every price is quoted 'starting at' with no published dose table — the rate can move as you titrate
  • Compounded medication is unavailable in six states and DC, and the overall coverage footprint is not published anywhere on the site

Sesame Care

Ranked #4 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Alloy nor Sesame Care is only worth comparing with the other. Alloy is also written up against CoreAge Rx, 11 points apart on the Luna Fit Score — see Alloy vs CoreAge Rx for women. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.

Or browse the full comparison hub.