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Head-to-head for women

Cielo vs Enhance MD

Cielo and Enhance MD both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Cielo

Ranked #50 for women · Grade C

Best for: Women who want a single-purpose GLP-1 program without a multi-vertical storefront attached, and who will check their own state before signing up.

Visit Cielo
vs

Enhance MD

Higher score

Ranked #2 for women · Grade A−

Best for: Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes.

Visit Enhance MD

The verdict for women

Higher Luna Fit Score: Enhance MD

Enhance MD edges out Cielo on the Luna Fit Score, 92 to 73 (A− vs C). Women who want fully transparent tiered pricing — including a microdose entry and a combo option — plus recurring metabolic lab work, and who don't need brand-name or oral routes. The reasoning behind that number is in the Enhance MD scorecard.

Cielo is still a genuine option — a deliberately narrow program — two GLP-1s and nothing else, no hair, no testosterone, no upsells — priced the same at every dose, but it publishes neither its coverage map nor its cancellation terms. Weigh the six women's-health factors below against your own priorities; the Cielo scorecard goes through each of them, and if neither of these two is the one, what women pick instead of Cielo widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Cielo Enhance MD
PCOS & hormonal suitability7492
Cielo
Enhance
Clinical oversight & labs7494
Cielo
Enhance
Price transparency7694
Cielo
Enhance
Nationwide access7095
Cielo
Enhance
Ongoing support8088
Cielo
Enhance
Cancellation fairness6285
Cielo
Enhance

Price, access & features

DetailCieloEnhance MD
Luna Fit Score73/100 · C92/100 · A−
Overall rank#50#2
Semaglutide$139/mo month-to-month (from $89/mo on a 6-month plan), same price any dose$212/mo
Tirzepatide$189/mo month-to-month (from $129/mo on a 6-month plan), same price any dose$280/mo
CoverageNot disclosedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only

Cielo

Ranked #50 · Grade C

What we like

  • Compounded semaglutide and tirzepatide are the entire product line, so nothing is being cross-sold alongside the prescription
  • 'Same price any dose' is stated plainly on both drug pages
  • Clinical care is contracted to MD Integrations, named in the terms of service rather than described vaguely

The caveats

  • Coverage is not disclosed anywhere — no state count, no nationwide claim, nothing in the terms
  • Cancellation, refund and auto-renewal terms are not published, which matters because the headline price needs a six-month plan
  • It is not stated whether the multi-month plans are prepaid

Enhance MD

Ranked #2 · Grade A−

What we like

  • Unusually transparent tiered pricing — semaglutide $212/mo (first month $112), tirzepatide $280/mo, microdose $169/mo, and a combo option at $322/mo
  • Dose-flat billing, so a titration up doesn't quietly raise your monthly cost
  • Six-month metabolic lab testing with provider oversight — a real clinical loop, not a prescription-only handoff

The caveats

  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • No brand-name path and no oral or sublingual route for the needle-averse
  • Licensed in all 50 states, though their own FAQ lists product as launched in 40 plus DC so far — worth confirming your state before you start

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Cielo nor Enhance MD is only worth comparing with the other. Cielo is also written up against CoreAge Rx, 20 points apart on the Luna Fit Score — see Cielo against CoreAge Rx, factor by factor. Enhance MD is also written up against CoreAge Rx, 1 point apart — see the Enhance MD–CoreAge Rx head-to-head.

Or browse the full comparison hub.