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Head-to-head for women

Cielo vs Trimi

Cielo and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Cielo

Ranked #50 for women · Grade C

Best for: Women who want a single-purpose GLP-1 program without a multi-vertical storefront attached, and who will check their own state before signing up.

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vs

Trimi

Higher score

Ranked #8 for women · Grade B

Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.

Visit Trimi

The verdict for women

Higher Luna Fit Score: Trimi

Trimi edges out Cielo on the Luna Fit Score, 84 to 73 (B vs C). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes. The reasoning behind that number is in what we found reviewing Trimi.

Cielo is still a genuine option — a deliberately narrow program — two GLP-1s and nothing else, no hair, no testosterone, no upsells — priced the same at every dose, but it publishes neither its coverage map nor its cancellation terms. Weigh the six women's-health factors below against your own priorities; the Cielo scorecard goes through each of them, and if neither of these two is the one, what women pick instead of Cielo widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Cielo Trimi
PCOS & hormonal suitability7484
Cielo
Trimi
Clinical oversight & labs7478
Cielo
Trimi
Price transparency7692
Cielo
Trimi
Nationwide access7090
Cielo
Trimi
Ongoing support8080
Cielo
Trimi
Cancellation fairness6280
Cielo
Trimi

Price, access & features

DetailCieloTrimi
Luna Fit Score73/100 · C84/100 · B
Overall rank#50#8
Semaglutide$139/mo month-to-month (from $89/mo on a 6-month plan), same price any dose$129/mo
Tirzepatide$189/mo month-to-month (from $129/mo on a 6-month plan), same price any dose$229/mo
CoverageNot disclosedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only

Cielo

Ranked #50 · Grade C

What we like

  • Compounded semaglutide and tirzepatide are the entire product line, so nothing is being cross-sold alongside the prescription
  • 'Same price any dose' is stated plainly on both drug pages
  • Clinical care is contracted to MD Integrations, named in the terms of service rather than described vaguely

The caveats

  • Coverage is not disclosed anywhere — no state count, no nationwide claim, nothing in the terms
  • Cancellation, refund and auto-renewal terms are not published, which matters because the headline price needs a six-month plan
  • It is not stated whether the multi-month plans are prepaid

Trimi

Ranked #8 · Grade B

What we like

  • Among the lowest published prices we track on both semaglutide and tirzepatide
  • Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
  • Nationwide across all 50 states with free shipping

The caveats

  • Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
  • Injectable only — no oral or sublingual route for the needle-averse
  • Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Cielo nor Trimi is only worth comparing with the other. Cielo is also written up against CoreAge Rx, 20 points apart on the Luna Fit Score — see Cielo against CoreAge Rx, factor by factor. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.

Or browse the full comparison hub.