Head-to-head for women
RxSpan MD vs Trimi
RxSpan MD and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
RxSpan MD
Ranked #19 for women · Grade B−
Luna Fit
Best for: Women who want to be able to check the pharmacy and the prescriber before they buy, and who may want to move between compounded, oral and brand-name options on one account — provided they pick the Monthly plan themselves rather than accepting the prepay the funnel has already selected.
Visit RxSpan MDTrimi
Higher scoreRanked #7 for women · Grade B
Luna Fit
Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.
Visit TrimiThe verdict for women
Trimi edges out RxSpan MD on the Luna Fit Score, 84 to 81 (B vs B−). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes. The reasoning behind that number is in what we found reviewing Trimi.
RxSpan MD is still a genuine option — one of the very few programs here that will tell you who compounds your medication and who signs the prescription — four pharmacies named with phone numbers, two physicians named with NPIs that resolve — wrapped around a full menu that runs from compounded semaglutide to brand Zepbound. Weigh the six women's-health factors below against your own priorities; our RxSpan MD write-up for women goes through each of them, and if neither of these two is the one, the full field we rank against RxSpan MD widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | RxSpan MD | Trimi |
|---|---|---|
| Luna Fit Score | 81/100 · B− | 84/100 · B |
| Overall rank | #19 | #7 |
| Semaglutide | $249/mo month-to-month (3/6/12-month prepay: $219/$199/$194 per month, billed $657/$1,194/$2,327 up front) | $175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge) |
| Tirzepatide | $329/mo month-to-month (3/6/12-month prepay: $309/$289/$269 per month, billed $927/$1,734/$3,228 up front) | $235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Yes | Injection only |
Luna Fit
RxSpan MD
Ranked #19 · Grade B−
What we like
- Four dispensing pharmacies named outright, with phone numbers — Belmar, Strive, Epiq Scripts and Casa Pharma Rx — where most of this ranking says only "our partner pharmacies"
- The prescribing group is named too, and checkable: Lion MD, led by Dr Ana Lisa Carr, MD (NPI 1689841744) with Dr Kelly Tenbrink, MD (NPI 1346482684). Both resolve as active physicians in the federal NPPES registry
- A real brand-name lane with prices on the page rather than an enquiry form — Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069 a month — alongside the compounded line, so switching does not mean switching provider
The caveats
- The plan selector arrives with the 3-month prepay already chosen, not Monthly, and badges the 3-, 6- and 12-month tiers alike as "Max Saving" — so the default path takes $657 up front rather than $249, and the headline figures are footnoted "(For the first month)"
- Its FAQ says "no long-term commitments" on the same site where the 12-month semaglutide plan is a single $2,327 charge and the 12-month tirzepatide plan is $3,228. The freedom is real on the monthly plan; it is not what the prepay tiers are
- Brand-name bundles carry a $50 medical review fee if a clinician does not end up prescribing for you — worth knowing before you start an intake for Wegovy or Zepbound
Luna Fit
Trimi
Ranked #7 · Grade B
What we like
- Among the lowest published prices we track on both semaglutide and tirzepatide
- Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
- Nationwide across all 50 states with free shipping
The caveats
- Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
- Injectable only — no oral or sublingual route for the needle-averse
- Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither RxSpan MD nor Trimi is only worth comparing with the other. RxSpan MD is also written up against CoreAge Rx, 12 points apart on the Luna Fit Score — see the RxSpan MD–CoreAge Rx head-to-head. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.
- RxSpan MD vs CoreAge Rx
- RxSpan MD vs Enhance MD
- RxSpan MD vs yourEra
- Trimi vs Sesame Care
- Trimi vs HealthRX
- Trimi vs MadeMed
Or browse the full comparison hub.