Head-to-head for women
RxSpan MD vs Vaylen
RxSpan MD and Vaylen both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
RxSpan MD
Ranked #19 for women · Grade B−
Luna Fit
Best for: Women who want to be able to check the pharmacy and the prescriber before they buy, and who may want to move between compounded, oral and brand-name options on one account — provided they pick the Monthly plan themselves rather than accepting the prepay the funnel has already selected.
Visit RxSpan MDVaylen
Higher scoreRanked #22 for women · Grade B+
Luna Fit
Best for: Women who want maximum optionality — injectable or oral, compounded or brand — from an accredited, all-50-states provider.
Visit VaylenThe verdict for women
Vaylen edges out RxSpan MD on the Luna Fit Score, 87 to 81 (B+ vs B−). Women who want maximum optionality — injectable or oral, compounded or brand — from an accredited, all-50-states provider. The reasoning behind that number is in what we found reviewing Vaylen.
RxSpan MD is still a genuine option — one of the very few programs here that will tell you who compounds your medication and who signs the prescription — four pharmacies named with phone numbers, two physicians named with NPIs that resolve — wrapped around a full menu that runs from compounded semaglutide to brand Zepbound. Weigh the six women's-health factors below against your own priorities; our RxSpan MD write-up for women goes through each of them, and if neither of these two is the one, the full field we rank against RxSpan MD widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | RxSpan MD | Vaylen |
|---|---|---|
| Luna Fit Score | 81/100 · B− | 87/100 · B+ |
| Overall rank | #19 | #22 |
| Semaglutide | $249/mo month-to-month (3/6/12-month prepay: $219/$199/$194 per month, billed $657/$1,194/$2,327 up front) | $179/mo |
| Tirzepatide | $329/mo month-to-month (3/6/12-month prepay: $309/$289/$269 per month, billed $927/$1,734/$3,228 up front) | $239/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
Luna Fit
RxSpan MD
Ranked #19 · Grade B−
What we like
- Four dispensing pharmacies named outright, with phone numbers — Belmar, Strive, Epiq Scripts and Casa Pharma Rx — where most of this ranking says only "our partner pharmacies"
- The prescribing group is named too, and checkable: Lion MD, led by Dr Ana Lisa Carr, MD (NPI 1689841744) with Dr Kelly Tenbrink, MD (NPI 1346482684). Both resolve as active physicians in the federal NPPES registry
- A real brand-name lane with prices on the page rather than an enquiry form — Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069 a month — alongside the compounded line, so switching does not mean switching provider
The caveats
- The plan selector arrives with the 3-month prepay already chosen, not Monthly, and badges the 3-, 6- and 12-month tiers alike as "Max Saving" — so the default path takes $657 up front rather than $249, and the headline figures are footnoted "(For the first month)"
- Its FAQ says "no long-term commitments" on the same site where the 12-month semaglutide plan is a single $2,327 charge and the 12-month tirzepatide plan is $3,228. The freedom is real on the monthly plan; it is not what the prepay tiers are
- Brand-name bundles carry a $50 medical review fee if a clinician does not end up prescribing for you — worth knowing before you start an intake for Wegovy or Zepbound
Luna Fit
Vaylen
Ranked #22 · Grade B+
What we like
- Offers an oral/sublingual route as well as injections — real choice for the needle-averse
- FDA-approved brand access plus compounded on both molecules
- LegitScript-accredited and available in all 50 states
The caveats
- Mid-tier pricing rather than the cheapest tiers
- Broad program rather than a dedicated PCOS/hormone clinic
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither RxSpan MD nor Vaylen is only worth comparing with the other. RxSpan MD is also written up against CoreAge Rx, 12 points apart on the Luna Fit Score — see the RxSpan MD–CoreAge Rx head-to-head. Vaylen is also written up against Effecty, another exact tie — see the Vaylen–Effecty head-to-head.
- RxSpan MD vs CoreAge Rx
- RxSpan MD vs Enhance MD
- RxSpan MD vs yourEra
- Vaylen vs Sesame Care
- Vaylen vs HealthRX
- Vaylen vs MadeMed
Or browse the full comparison hub.