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Head-to-head for women

System Labs vs Trimi

System Labs and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

System Labs

Ranked #18 for women · Grade B−

Best for: Women who want one predictable monthly cost that does not climb as they titrate, and who are comfortable with a single compounded GLP-1/GIP injection rather than a choice of named molecules.

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vs

Trimi

Higher score

Ranked #8 for women · Grade B

Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.

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The verdict for women

Higher Luna Fit Score: Trimi

Trimi edges out System Labs on the Luna Fit Score, 84 to 81 (B vs B−). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.

System Labs is still a genuine option — a flat $179 a month at every dose, with the ongoing rate stated in writing rather than buried under an intro price — and you can cancel from your own dashboard, which is more than most of this board will commit to. Weigh the six women's-health factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

System Labs Trimi
PCOS & hormonal suitability7884
System
Trimi
Clinical oversight & labs8278
System
Trimi
Price transparency8492
System
Trimi
Nationwide access7490
System
Trimi
Ongoing support8480
System
Trimi
Cancellation fairness8880
System
Trimi

Price, access & features

DetailSystem LabsTrimi
Luna Fit Score81/100 · B−84/100 · B
Overall rank#18#8
SemaglutideNot disclosed$129/mo
TirzepatideGLP-1/GIP $179/mo flat ($99 first month)$229/mo
CoverageNot publicly listedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only

System Labs

Ranked #18 · Grade B−

What we like

  • One flat price at every dose — the plan is sold as a "Monthly Supply (All doses)", so titrating up does not quietly raise the bill
  • The ongoing rate is stated, not implied: their own FAQ says the subscription is billed at a flat $179/mo with no hidden fees
  • Pause or cancel yourself from the dashboard at any time — no phone call, no retention queue

The caveats

  • Compounded medication is not FDA-approved, and the site says so plainly in its own FDA disclosure
  • The molecule is never named — it is sold only as "compounded GLP-1/GIP", so you cannot compare it against a semaglutide or tirzepatide price anywhere else on this board
  • The headline price is a first-month teaser: $99 for month one against a $179 standing rate, so budget for $179 rather than the number in the hero

Trimi

Ranked #8 · Grade B

What we like

  • Among the lowest published prices we track on both semaglutide and tirzepatide
  • Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
  • Nationwide across all 50 states with free shipping

The caveats

  • Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
  • Injectable only — no oral or sublingual route for the needle-averse
  • Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing System Labs and Trimi against other providers we review for women.

Or browse the full comparison hub.