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Head-to-head for women
System Labs vs Trimi
System Labs and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
System Labs
Ranked #18 for women · Grade B−
Luna Fit
Best for: Women who want one predictable monthly cost that does not climb as they titrate, and who are comfortable with a single compounded GLP-1/GIP injection rather than a choice of named molecules.
Visit System LabsTrimi
Higher scoreRanked #8 for women · Grade B
Luna Fit
Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.
Visit TrimiThe verdict for women
Trimi edges out System Labs on the Luna Fit Score, 84 to 81 (B vs B−). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes. The reasoning behind that number is in what we found reviewing Trimi.
System Labs is still a genuine option — a flat $179 a month at every dose, with the ongoing rate stated in writing rather than buried under an intro price — and you can cancel from your own dashboard, which is more than most of this ranking will commit to. Weigh the six women's-health factors below against your own priorities; our System Labs write-up for women goes through each of them, and if neither of these two is the one, the alternatives to System Labs we rank for women widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | System Labs | Trimi |
|---|---|---|
| Luna Fit Score | 81/100 · B− | 84/100 · B |
| Overall rank | #18 | #8 |
| Semaglutide | Not offered — the one GLP-1 product is a compounded GLP-1/GIP and no semaglutide is sold | $175/mo month-to-month · $99/mo only on a 12-month prepay ($1,188 in one charge) |
| Tirzepatide | GLP-1/GIP $179/mo flat ($99 first month) | $235/mo month-to-month · $125/mo only on a 12-month prepay ($1,500 in one charge) |
| Coverage | Not publicly listed | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Luna Fit
System Labs
Ranked #18 · Grade B−
What we like
- One flat price at every dose — the plan is sold as a "Monthly Supply (All doses)", so titrating up does not quietly raise the bill
- The ongoing rate is stated, not implied: their own FAQ says the subscription is billed at a flat $179/mo with no hidden fees
- Pause or cancel yourself from the dashboard at any time — no phone call, no retention queue
The caveats
- Compounded medication is not FDA-approved, and the site says so plainly in its own FDA disclosure
- The molecule is never named — it is sold only as "compounded GLP-1/GIP", so you cannot compare it against a semaglutide or tirzepatide price anywhere else in this ranking
- The headline price is a first-month teaser: $99 for month one against a $179 standing rate, so budget for $179 rather than the number in the hero
Luna Fit
Trimi
Ranked #8 · Grade B
What we like
- Among the lowest published prices we track on both semaglutide and tirzepatide
- Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
- Nationwide across all 50 states with free shipping
The caveats
- Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
- Injectable only — no oral or sublingual route for the needle-averse
- Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither System Labs nor Trimi is only worth comparing with the other. System Labs is also written up against CoreAge Rx, 12 points apart on the Luna Fit Score — see the System Labs–CoreAge Rx head-to-head. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.
- System Labs vs CoreAge Rx
- System Labs vs Enhance MD
- System Labs vs Eden
- Trimi vs yourEra
- Trimi vs Sesame Care
- Trimi vs HealthRX
Or browse the full comparison hub.