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Head-to-head for women

Cielo vs Sesame Care

Cielo and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.

Cielo

Ranked #50 for women · Grade C

Best for: Women who want a single-purpose GLP-1 program without a multi-vertical storefront attached, and who will check their own state before signing up.

Visit Cielo
vs

Sesame Care

Higher score

Ranked #4 for women · Grade B

Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.

Visit Sesame Care

The verdict for women

Higher Luna Fit Score: Sesame Care

Sesame Care edges out Cielo on the Luna Fit Score, 85 to 73 (B vs C). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.

Cielo is still a genuine option — a deliberately narrow program — two GLP-1s and nothing else, no hair, no testosterone, no upsells — priced the same at every dose, but it publishes neither its coverage map nor its cancellation terms. Weigh the six women's-health factors below against your own priorities; the Cielo scorecard goes through each of them, and if neither of these two is the one, what women pick instead of Cielo widens the field.

Side-by-side on the six factors

Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.

Cielo Sesame Care
PCOS & hormonal suitability7484
Cielo
Sesame
Clinical oversight & labs7488
Cielo
Sesame
Price transparency7680
Cielo
Sesame
Nationwide access7092
Cielo
Sesame
Ongoing support8082
Cielo
Sesame
Cancellation fairness6285
Cielo
Sesame

Price, access & features

DetailCieloSesame Care
Luna Fit Score73/100 · C85/100 · B
Overall rank#50#4
Semaglutide$139/mo month-to-month (from $89/mo on a 6-month plan), same price any doseFrom $149/mo (brand Wegovy pill)
Tirzepatide$189/mo month-to-month (from $129/mo on a 6-month plan), same price any doseBrand Zepbound (price varies)
CoverageNot disclosedNationwide marketplace
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes

Cielo

Ranked #50 · Grade C

What we like

  • Compounded semaglutide and tirzepatide are the entire product line, so nothing is being cross-sold alongside the prescription
  • 'Same price any dose' is stated plainly on both drug pages
  • Clinical care is contracted to MD Integrations, named in the terms of service rather than described vaguely

The caveats

  • Coverage is not disclosed anywhere — no state count, no nationwide claim, nothing in the terms
  • Cancellation, refund and auto-renewal terms are not published, which matters because the headline price needs a six-month plan
  • It is not stated whether the multi-month plans are prepaid

Sesame Care

Ranked #4 · Grade B

What we like

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency

The caveats

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Neither Cielo nor Sesame Care is only worth comparing with the other. Cielo is also written up against CoreAge Rx, 20 points apart on the Luna Fit Score — see Cielo against CoreAge Rx, factor by factor. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.

Or browse the full comparison hub.