Head-to-head for women
NewSelf vs Trimi
NewSelf and Trimi both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
NewSelf
Ranked #54 for women · Grade C
Luna Fit
Best for: Women who are certain they want three months of a flat-priced compounded GLP-1 and will not need to change their mind, because changing it is expensive here.
Visit NewSelfTrimi
Higher scoreRanked #8 for women · Grade B
Luna Fit
Best for: Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes.
Visit TrimiThe verdict for women
Trimi edges out NewSelf on the Luna Fit Score, 84 to 64 (B vs C). Cost-conscious women who want nationwide access to both molecules — including tirzepatide for insulin-resistant PCOS — at the lowest sticker price, and who don't need brand-name or oral routes. The reasoning behind that number is in what we found reviewing Trimi.
NewSelf is still a genuine option — one price at any dose, three months of medication shipped up front — and a set of exit terms and unresolved compliance problems that make it the hardest program on this board to leave. Weigh the six women's-health factors below against your own priorities; our NewSelf write-up for women goes through each of them, and if neither of these two is the one, our ranked shortlist of NewSelf alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | NewSelf | Trimi |
|---|---|---|
| Luna Fit Score | 64/100 · C | 84/100 · B |
| Overall rank | #54 | #8 |
| Semaglutide | $134.99/mo flat at every dose (as low as $99.97; 3-month term required) | $129/mo |
| Tirzepatide | $224.99/mo flat at every dose (as low as $144.49; 3-month term required) | $229/mo |
| Coverage | 48 states and Puerto Rico (not Mississippi or Louisiana) | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Luna Fit
NewSelf
Ranked #54 · Grade C
What we like
- One flat price at every dose for both molecules, with the dose ladder published beside it
- Three months of medication shipped up front, so there is no waiting on refills mid-titration
- LegitScript certified with a published, checkable ID
The caveats
- FDA warning letter MARCS-CMS 721472, dated 20 February 2026, to NewSelf Limited dba NewSelf, over product labelling and marketing language. As of 1 August 2026 the wording the FDA objected to was still live on the site — five months on, unremediated
- The product pages carry a badge reading 'cancel anytime', while the refund policy requires a three-month commitment and charges a full retail month as an early-cancellation fee. Those cannot both be true
- No refunds: cancelling before the doctor's review costs a $99 administrative fee, and after it nothing is refundable regardless of shipment status
Luna Fit
Trimi
Ranked #8 · Grade B
What we like
- Among the lowest published prices we track on both semaglutide and tirzepatide
- Both molecules on one membership — tirzepatide matters where insulin resistance drives PCOS weight
- Nationwide across all 50 states with free shipping
The caveats
- Compounded only — no FDA-approved Ozempic/Wegovy or Mounjaro/Zepbound
- Injectable only — no oral or sublingual route for the needle-averse
- Dispensing pharmacy isn't publicly named, so the third-party oversight signal is thinner
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither NewSelf nor Trimi is only worth comparing with the other. NewSelf is also written up against CoreAge Rx, 29 points apart on the Luna Fit Score — see the NewSelf–CoreAge Rx head-to-head. Trimi is also written up against CoreAge Rx, 9 points apart — see Trimi vs CoreAge Rx for women.
- NewSelf vs CoreAge Rx
- NewSelf vs Enhance MD
- NewSelf vs yourEra
- Trimi vs Sesame Care
- Trimi vs HealthRX
- Trimi vs Strut Health
Or browse the full comparison hub.